Results 131 to 140 of about 50,235 (294)

Regression dilution methods for meta-analysis: assessing long-term variability in plasma fibrinogen among 27 247 adults in 15 prospective studies

open access: yes, 2006
BACKGROUND: Within-person variability in measured values of a risk factor can bias its association with disease. The extent of this regression dilution bias for plasma fibrinogen was investigated using repeat measurement data collected at varying time ...
White, I   +11 more
core   +1 more source

Living at genetic risk: The patient experience of Lynch syndrome

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Lynch syndrome is a germline cancer predisposition syndrome caused by a variant in one of four genes. Lynch syndrome places individuals at significantly higher risk for a range of cancers, especially colorectal and endometrial. Depending on which gene is affected, the risk of ovarian, gastric, small bowel, pancreatic, biliary urothelial, brain,
Nicola Reents   +2 more
wiley   +1 more source

The Critical Period for Neuroprotection by Estrogen Replacement Therapy and the Potential Underlying Mechanisms. [PDF]

open access: yesCurr Neuropharmacol, 2020
Guo H   +6 more
europepmc   +1 more source

Age at First Pregnancy, Adult Weight Gain and Postmenopausal Breast Cancer Risk: The PROCAS Study (United Kingdom)

open access: yesInternational Journal of Cancer, EarlyView.
An early first pregnancy is protective against postmenopausal breast cancer. However, pregnancy is also a key contributor to weight gain, and adult weight gain increases postmenopausal breast cancer risk. This prospective cohort study quantified the combined effect of adult weight gain and age at first pregnancy on postmenopausal breast cancer risk ...
Lee Malcomson   +7 more
wiley   +1 more source

Associations of Outdoor Air Pollution With Incidence of Cancers Other Than Lung Cancer in a Large US Prospective Cohort

open access: yesInternational Journal of Cancer, EarlyView.
Associations between outdoor air pollution and cancers other than lung cancer remain unclear, particularly in the context of tobacco use. Here, the authors assessed possible links between ambient air pollutant exposure and incidence of 20 non‐lung cancers among adults followed over a 25‐year period in the United States.
W. Ryan Diver   +4 more
wiley   +1 more source

Effect of estrogens on skin aging and the potential role of SERMs

open access: yesClinical Interventions in Aging, 2007
Susan Stevenson1, Julie Thornton21Burns & Plastic Surgery Research Unit, 2Cutaneous Research, Medical Biosciences, School of Life Sciences, University of Bradford, Bradford, UKAbstract: In humans, structural and functional changes attributable to ...
Susan Stevenson, Julie Thornton
doaj  

Clinical Implementation and Oncological Relevance of Molecular Profiling in Brain Metastases Patients—A Multicenter Retrospective Cohort Study

open access: yesInternational Journal of Cancer, EarlyView.
While current guidelines recommend the analysis of established cancer driver genes in brain metastases, little is known about its real‐life implementation. This multicenter study revealed an upward trend in the profiling rates of surgically treated brain metastases over the past decade, with up to 60% of brain metastases samples undergoing analysis ...
Maria Nikolaeva   +25 more
wiley   +1 more source

Optimizing outcomes in intrauterine insemination: A narrative synthesis of two decades of clinical research (2000–2024)

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Intrauterine insemination (IUI) is a widely used first‐line fertility treatment, yet its success rates vary considerably. This review synthesizes evidence from peer‐reviewed studies published between 2000 and 2024, including randomized controlled trials, cohort and case–control studies, as well as systematic and narrative reviews identified ...
Kasuni Akalanka
wiley   +1 more source

Luteal phase stimulation versus follicular phase stimulation in poor ovarian responders: A systematic review and a meta‐analysis

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Poor ovarian response (POR) complicates a substantial proportion of in vitro fertilization (IVF) cycles, frequently causing cycle cancellation and suboptimal reproductive outcomes. Conventional follicular‐phase ovarian stimulation (FPOS) protocols often yield limited results, prompting the evaluation of alternative strategies such ...
Vittorio Agrifoglio   +8 more
wiley   +1 more source

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