ABSTRACT Background Elinzanetant, a novel, dual neurokinin‐targeted therapy, has been approved in various geographies for the treatment of moderate‐to‐severe vasomotor symptoms (VMS) associated with menopause. Objective To compare the efficacy of elinzanetant with non‐hormonal pharmaceutical treatments (nHT) in alleviating VMS.
Piotr Wojciechowski +8 more
wiley +1 more source
The role of sex as a biological variable in neurocritical care: Fundamentals of cerebrovascular physiology with clinical implications. [PDF]
Maier LE +3 more
europepmc +1 more source
ABSTRACT Background The transition through menopause is accompanied by a series of adverse metabolic changes which are associated with an increased risk of cardiometabolic disease, a major cause of mortality in women after midlife. Whilst the indication for menopausal hormone replacement therapy (HRT) is the control of menopausal symptoms ...
Jiawen Dong +5 more
wiley +1 more source
Therapeutic approaches for endocrine dysregulation in anorexia nervosa in adolescents. [PDF]
Hoskens L +3 more
europepmc +1 more source
Factors Associated With Menopause Symptoms: A Systematic Review and Meta‐Analysis
ABSTRACT Background Menopause, marked by hormonal decline and menstrual cessation, is associated with various symptoms. Socio‐demographic and behavioural factors may influence symptom type and severity. Understanding these associations can inform better symptom management.
Janice Hoang +10 more
wiley +1 more source
Oral contraceptives and tissue factor expression. Comments on "Do combined oral contraceptives induce formation of tissue factor?" [PDF]
Østerud B.
europepmc +1 more source
Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas +3 more
wiley +1 more source
When Lifelong Anosmia Reveals Hypogonadism: A Case of Kallmann Syndrome with Primary Amenorrhea. [PDF]
Lubis JYG +3 more
europepmc +1 more source
ABSTRACT Introduction We aimed to assess diagnostic performance and accuracy for local staging of CEM combined with DBT (CE + DBT) compared to digital mammography (DM) and MRI. Methods Female patients aged 18–70 years with clinical or sonographic suspicion of breast cancer had CE + DBT and breast MRI prior to treatment.
Sarah L. Savaridas +7 more
wiley +1 more source
Cardiovascular and metabolic outcomes of GH replacement therapy in adults with GH deficiency - gender gaps. [PDF]
Milioto A +3 more
europepmc +1 more source

