Treatment of symptoms of the menopause: an endocrine society clinical practice guideline [PDF]
Objective: The objective of this document is to generate a practice guideline for the management and treatment of symptoms of the menopause. Participants: The Treatment of Symptoms of the Menopause Task Force included six experts, a methodologist, and
Davis, Susan R.+6 more
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Weak if any effect of estrogen on spatial memory in rats [PDF]
In a number of species, males appear to have spatial abilities that are superior to those of females. The favored explanation for this cognitive difference is hormonal: higher testosterone levels in males than in females.
Farkas, Tamás+5 more
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Duplicated membrane estrogen receptors in the European sea bass (Dicentrarchus labrax): Phylogeny, expression and regulation throughout the reproductive cycle [PDF]
The numerous estrogen functions reported across vertebrates have been classically explained by their binding to specific transcription factors, the nuclear estrogen receptors (ERs).
Alvarado, M. Victoria+5 more
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The serotonin transporter promotes a pathological estrogen metabolic pathway in pulmonary hypertension via cytochrome P450 1B1 pulmonary circulation [PDF]
Pulmonary arterial hypertension (PAH) is a devastating vasculopathy that predominates in women and has been associated with dysregulated estrogen and serotonin signaling. Overexpression of the serotonin transporter (SERT+) in mice results in an estrogen-
Anagnostopoulou, Aikaterini+9 more
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Reference Profile Correlation Reveals Estrogen-like Trancriptional Activity of Curcumin [PDF]
Background: Several secondary metabolites from herbal nutrient products act as weak estrogens (phytoestrogens), competing with endogenous estrogen for binding to the estrogen receptors and inhibiting steroid converting enzymes.
Albini, Adriana+9 more
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Gender in endocrine diseases: role of sex gonadal hormones [PDF]
Gender- and sex- related differences represent a new frontier towards patient-tailored medicine, taking into account that theoretically every medical specialty can be influenced by both of them.
Appetecchia, M.+4 more
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Pyrolysis of Wastewater Biosolids Significantly Reduces Estrogenicity [PDF]
Most wastewater treatment processes are not specifically designed to remove micropollutants. Many micropollutants are hydrophobic so they remain in the biosolids and are discharged to the environment through land-application of biosolids. Micropollutants
Hoffman, T. C.+2 more
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Urinary estrogen metabolites and prostate cancer : a case-control study and meta-analysis [PDF]
Objective: To investigate prostate cancer (Pca) risk in relation to estrogen metabolism, expressed as urinary 2-hydroxyestrone (2-OHE1), 16α-hydroxyestrone (16α-OHE1) and 2-OHE1 to 16α-OHE1 ratio.
Barba, Maddalena+11 more
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New approaches for estimating risk from exposure to diethylstilbestrol. [PDF]
A subgroup from a National Institute of Environmental Health Sciences, workshop concerned with characterizing the effects of endocrine disruptors on human health at environmental exposure levels considered the question, If diethylstilbestrol (DES) were ...
Cunha, GR+7 more
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Influence of sex differences on microRNA gene regulation in disease. [PDF]
Sexual dimorphism is observed in most human diseases. The difference in the physiology and genetics between sexes can contribute tremendously to the disease prevalence, severity, and outcome.
Eghbali, Mansoureh, Sharma, Salil
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