Results 41 to 50 of about 91,779 (299)

Environmental exposure of steroid estrogens and their migration and transformation behavior

open access: yes浙江大学学报. 农业与生命科学版, 2017
Steroid estrogens are a group of biologically active compounds synthesized from cholesterol and have a cyclopentan-o-perhydrophenanthrene ring in common.
TONG Xin   +6 more
doaj   +1 more source

Estrogenic Activities in Rodent Estrogen-Free Diets [PDF]

open access: yesEndocrinology, 2005
Diets lacking soy and alpha-alpha derivatives that are considered to be estrogen-free by standard bioassays (uterotrophic assay and vaginal opening) have been revealed to contain considerable amounts of compounds able to transcriptionally activate the estrogen receptors (ERs) and stimulate luciferase expression in several organs of the ERE-Luc reporter
P. Ciana   +5 more
openaire   +3 more sources

Select estrogens within the complex formulation of conjugated equine estrogens (Premarin®) are protective against neurodegenerative insults: implications for a composition of estrogen therapy to promote neuronal function and prevent Alzheimer's disease

open access: yesBMC Neuroscience, 2006
Background Results of the Women's Health Initiative Memory Study (WHIMS) raised concerns regarding the timing and formulation of hormone interventions.
Brinton Roberta, Zhao Liqin
doaj   +1 more source

Signaling by estrogens [PDF]

open access: yesJournal of Cellular Physiology, 2007
AbstractBy regulating activities and expression levels of key signaling molecules, estrogens control mechanisms that are responsible for crucial cellular functions. Ligand binding to estrogen receptor (ER) leads to conformational changes that regulate the receptor activity, its interaction with other proteins and DNA.
Boris J, Cheskis   +3 more
openaire   +2 more sources

Inhibition of Androgen-Independent Prostate Cancer by Estrogenic Compounds Is Associated with Increased Expression of Immune-Related Genes

open access: yesNeoplasia: An International Journal for Oncology Research, 2006
The clinical utility of estrogens for treating prostate cancer (CaP) was established in the 1940s by Huggins. The classic model of the anti-CaP activity of estrogens postulates an indirect mechanism involving the suppression of androgen production ...
Ilsa M. Coleman   +7 more
doaj   +1 more source

Estrogens in schizophrenia: What do we know?

open access: yesEuropean Psychiatry, 2021
Introduction Schizophrenia is a chronic disease that significantly impacts cognitive functioning. Sex differences in incidence, onset and course of schizophrenia suggest estrogens have a protective role.
L. Paulino Ferreira   +3 more
doaj   +1 more source

Algal extracellular organic matter mediated photocatalytic degradation of estrogens

open access: yesEcotoxicology and Environmental Safety, 2021
Estrogens are among the most concerned emerging contaminants in the wastewater treatment effluent due to their sexual disruption in aquatic wildlife. The use of microalgae for secondary wastewater effluent polishing is a promising approach due to the ...
Pei-Hsun Wu   +4 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

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