Results 51 to 60 of about 136,462 (216)

Equine estrogens differentially inhibit DNA fragmentation induced by glutamate in neuronal cells by modulation of regulatory proteins involved in programmed cell death

BMC Neuroscience, 2003
Background Recent data indicate that excitotoxicity of high levels of neurotransmitter glutamate may be mediated via programmed cell death (apoptosis) and that it can be prevented in HT22 mouse hippocampal cells by various equine estrogens with Δ8,17β ...
Lu XiaoFeng, Zhang YueMei, Bhavnani Bhagu R   +2 more
doaj   +1 more source

Desenvolvimento de metodologia para avaliar remoção de estrogênios em estações de tratamento de esgotos

Química Nova, 2012
The present research aimed to study the parameters that affect the determination of estrogens in sewage upon the use of SPE and determination by using gas chromatography mass spectrometry (GC/MS).
Germana de Paiva Pessoa, André Bezerra dos Santos, Neyliane Costa de Souza, Joana Angélica Correia Alves, Ronaldo Ferreira do Nascimento   +4 more
doaj   +1 more source

Simultaneous determination of natural and synthetic steroid estrogens and their conjugates in aqueous matrices by liquid chromatography / mass spectrometry [PDF]

, 2005
An analytical method for the simultaneous determination of nine free and conjugated steroid estrogens was developed with application to environmental aqueous matrices.
Bean KA, Belfroid AC, Berg FD, Bowers LD, Bowers Sanaullah LD, Choi BK, Croley TR, Desbrow C, Diaz-Cruz MS, Dray J, D’Ascenzo G, Fotsis T, Fotsis T, Gangl ET, Gentilli A, Gomes RL, Gomes RL, Gomes RL, Hogenboom AC, Huang C-H, Huang C-H, Isobe T, Ito S, Jason W. Birkett, John N. Lester, Kanda R, King R, Kuch HM, Liang HR, Mallet CR, Mark D. Scrimshaw, Mouatassim–Souali A, Rachel L. Gomes, Ranney RE, Rodgers–Gray TP, Snyder SA, Steen R, Steimer T, Tabak HH, Tang PW, Ternes TA, Ternes TA, Thomas KV, Zhang H   +43 more
core   +1 more source

Estrogens and Stem Cells in Thyroid Cancer

Frontiers in Endocrinology, 2014
Recent discoveries highlight the emerging role of estrogens in the initiation and progression of different malignancies through their interaction with stem cell compartment.
Mariangela eZane, Mariangela eZane, Veronica eCatalano, Emanuela eScavo, Marco eBonanno, Maria Rosa Pelizzo, Matilde eTodaro, Giorgio eStassi   +7 more
doaj   +1 more source

The Effect of a Synthetic Estrogen, Ethinylestradiol, on the hERG Block by E-4031

Biomolecules, 2021
Inhibition of K+-conductance through the human ether-a-go-go related gene (hERG) channel leads to QT prolongation and is associated with cardiac arrhythmias.
Fumiya Tamura, Shintaro Sugimoto, Mana Sugimoto, Kazuho Sakamoto, Masahiko Yamaguchi, Takeshi Suzuki, Keiichi Fukuda, Masaki Ieda, Junko Kurokawa   +8 more
doaj   +1 more source

A–C Estrogens as Potent and Selective Estrogen Receptor-Beta Agonists (SERBAs) to Enhance Memory Consolidation under Low-Estrogen Conditions [PDF]

, 2018
Estrogen receptor-beta (ERβ) is a drug target for memory consolidation in postmenopausal women. Herein is reported a series of potent and selective ERβ agonists (SERBAs) with in vivo efficacy that are A–C estrogens, lacking the B and D estrogen rings ...
Donaldson, William A., Frick, Karyn M., Hanson, Alicia M., Imhoff, Andrea, Kim, Jaekyoon, Lu, Xingyun, Mackinnon, Alexander Craig, Pandey, Rajesh K., Perera, K. L. Iresha Sampathi, Sem, Daniel S., Sweeney, Noreena, Van Hart, Rochelle M., Wargolet, Adam J.   +12 more
core   +4 more sources

Metabolic alteration of circulating steroid hormones in women with gestational diabetes mellitus and the related risk factors

Frontiers in Endocrinology, 2023
BackgroundAbnormally changed steroid hormones during pregnancy are closely related to the pathological process of gestational diabetes mellitus (GDM). Our aim was to systematically profile the metabolic alteration of circulating steroid hormones in GDM ...
Na Yang, Na Yang, Wei Zhang, Cheng Ji, Jiajia Ge, Xiaoli Zhang, Meijuan Li, Min Wang, Tianqi Zhang, Jun He, Huaijun Zhu   +10 more
doaj   +1 more source

Pyrolysis of Wastewater Biosolids Significantly Reduces Estrogenicity [PDF]

, 2016
Most wastewater treatment processes are not specifically designed to remove micropollutants. Many micropollutants are hydrophobic so they remain in the biosolids and are discharged to the environment through land-application of biosolids. Micropollutants
Hoffman, T. C., McNamara, Patrick J., Zitomer, Daniel   +2 more
core   +1 more source

The MPA mouse breast cancer model: evidence for a role of progesterone receptors in breast cancer [PDF]

, 2009
More than 60% of all breast neoplasias are ductal carcinomas expressing estrogen (ER) and progesterone receptors (PR). In contrast, most of the spontaneous, chemically or MMTV induced tumors, as well as tumors arising in genetically modified mice do not ...
Bottino, Maria Cecilia, Cerliani, Juan Pablo, Fabris, Victoria Teresa, Giulianelli, Sebastian Jesus, Helguero, Luisa A., Lamb, Caroline Ana, Lanari, Claudia Lee Malvina, Molinolo, Alfredo, Soldati, Rocío, Wargon, Victoria   +9 more
core   +1 more source

Potassium, magnesium and pyridoxine in the context of the biological effects of estrogens [PDF]

Гинекология, 2017
Potassium and magnesium ions are essential for realizing the biological effects of estrogens. Magnesium ions promote the translocation of the estrogen receptors into the nucleus of the cell and regulate the potassium channels that are involved in the ...
O A Gromova, I Yu Torshin, I K Tomilova, L K Dzhidzhikhiya, N V Kerimkulova   +4 more
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