Results 71 to 80 of about 136,462 (216)

Protection of HT22 neuronal cells against chemically-induced ferroptosis by catechol estrogens: protein disulfide isomerase as a mechanistic target

Scientific Reports
Ferroptosis is a form of regulated cell death, characterized by excessive iron-dependent lipid peroxidation. Biochemically, ferroptosis can be selectively induced by erastin through glutathione depletion or through inhibition of glutathione peroxidase 4 ...
Xuanqi Huang, Ming-Jie Hou, Bao Ting Zhu
doaj   +1 more source

Measured body size and serum estrogen metabolism in postmenopausal women: the Ghana Breast Health Study

Breast Cancer Research, 2022
Background Several anthropometric measures have been associated with hormone-related cancers, and it has been shown that estrogen metabolism in postmenopausal women plays an important role in these relationships.
Ashley M. Geczik, Roni T. Falk, Xia Xu, Daniel Ansong, Joel Yarney, Beatrice Wiafe-Addai, Lawrence Edusei, Florence Dedey, Verna Vanderpuye, Nicholas Titiloye, Ernest Adjei, Francis Aitpillah, Ernest Osei-Bonsu, Joseph Oppong, Richard Biritwum, Kofi Nyarko, Seth Wiafe, Baffour Awuah, Joe-Nat Clegg-Lamptey, Thomas U. Ahearn, Jonine Figueroa, Montserrat Garcia-Closas, Louise A. Brinton, Britton Trabert   +23 more
doaj   +1 more source

Environmental Factors in the Relapse and Recurrence of Inflammatory Bowel Disease:A Review of the Literature [PDF]

, 2015
The causes of relapse in patients with Crohn's disease (CD) and ulcerative colitis (UC) are largely unknown. This paper reviews the epidemiological and clinical data on how medications (non-steroidal anti-inflammatory drugs, estrogens and antibiotics ...
A Bitton, A Bitton, A Dignass, A Kaser, A Lunderquist, A Timmer, AJ Wakefield, AM Meyer, AN Ananthakrishnan, Andrew R. Hart, AP Dhillon, B Boye, BD Levy, C Abraham, C Luong, C Mowat, CN Bernstein, CS Guerreiro, CS North, D Lader, DA Gorard, DC Baumgart, DC Baumgart, E Lindberg, E Stepien, EA Magee, EA Magee, EA Miles, EF Foley, EM Sternberg, F Backhed, F Casellas, FN Aberra, G Bonizzi, G Bouma, G Cipolla, G Savoye, GE Reese, GF Bonner, GP Chrousos, H Brunner, H Tornqvist, IC Solberg, J Cosnes, J Cosnes, J Cosnes, J Eaden, JA Dominitz, JA Mancini, JB Felder, JC Meijers, JM Evans, KJ Khan, KS Rothfuss, L Beaugerie, L Beaugerie, L LeResche, L Lu, LM Lichtenberger, LR Sutherland, LR Sutherland, M Aslam, M Cottone, M Dybdahl, MB Grisham, MC Aldhous, MC Pitcher, MN Merrett, MT Severinsen, NJ Simmonds, NP Thompson, O Hovde, OA Hatoum, P Seksik, PJ Loll, R Reid, R Schreck, RD Cohen, RK Linskens, RM Beattie, RS Barua, S Danese, S Hayashi, S Levenstein, S Parcell, S Sigaud, S Singh, S Zhang, Simon S. M. Chan, SL Jowett, SM Collins, SM Collins, SS Hecht, ST Smale, SU Christl, SV Kane, T Hisamatsu, THJ Florin, Thomas D. Martin, U Erikson   +99 more
core   +1 more source

The binding of estrogen and estrogen antagonists to the estrogen receptor

Archives of Biochemistry and Biophysics, 1992
The model of the estrogen receptor as a dimer of identical, interacting subunits and data obtained by Sasson and Notides (1988, Mol. Endocrinol. 2, 307-312) were used to find the standard free energy changes that describe the binding of estradiol and 4-hydroxytamoxifen to the estrogen receptor.
J P, Bond, S, Sasson, A C, Notides
openaire   +2 more sources

Mammographic breast density and its association with urinary estrogens and the fecal microbiota in postmenopausal women.

PLoS ONE, 2019
BackgroundBreast density, as estimated by mammography, is a strong risk factor for breast cancer in pre- and postmenopausal women, but the determinants of breast density have not yet been established.
Gieira S Jones, Heather Spencer Feigelson, Roni T Falk, Xing Hua, Jacques Ravel, Guoqin Yu, Roberto Flores, Mitchell H Gail, Jianxin Shi, Xia Xu, James J Goedert   +10 more
doaj   +1 more source

Immunolocalization of steroidogenic enzymes in the vaginal mucous of Galea spixii during the estrous cycle. [PDF]

, 2017
BackgroundThe synthesis of sex steroids is controlled by several enzymes such as17α-hydroxylase cytochrome P450 (P450c17) catalyzing androgen synthesis and aromatase cytochrome P450 (P450arom) catalyzing estrogen synthesis, both of which must complex ...
Assis Neto, Antônio Chaves de, Conley, Alan James, de Oliveira, Moacir Franco, Dos Santos, Amilton Cesar, Oliveira, Gleidson Benevides, Viana, Diego Carvalho   +5 more
core   +1 more source

A Network Meta‐Analysis of Efficacy of Different Interventions in the Prevention of Postoperative Intrauterine Adhesions

Clinical and Translational Science, 2020
This network meta‐analysis was conducted to compare the efficacy of six interventions, including anti‐blocking agents, intrauterine contraceptive devices (IUDs), estrogens, intrauterine balloon, Foley catheter, and amnion graft for the prevention of ...
Qian Xiong, Tiansong Zhang, Shujun Su
doaj   +1 more source

New approaches for estimating risk from exposure to diethylstilbestrol. [PDF]

, 1999
A subgroup from a National Institute of Environmental Health Sciences, workshop concerned with characterizing the effects of endocrine disruptors on human health at environmental exposure levels considered the question, If diethylstilbestrol (DES) were ...
Cunha, GR, Forsberg, JG, Golden, R, Haney, A, Iguchi, T, Newbold, R, Swan, S, Welshons, W   +7 more
core   +2 more sources

Breast cancer: estrogens as carcinogens

Zdravniški Vestnik, 2013
The major known risk factors for breast cancer are associated with a prolonged exposure to increased levels of estrogens and their reactive metabolites. The mechanisms through which estrogens contribute to the carcinogenic process are complex.
Jasmina-Živa Černe, Srdjan Novaković, Ksenija Geršak   +2 more
doaj  

Characterization of atrazine-induced gonadal malformations in African clawed frogs (Xenopus laevis) and comparisons with effects of an androgen antagonist (cyproterone acetate) and exogenous estrogen (17beta-estradiol): Support for the demasculinization/feminization hypothesis. [PDF]

, 2006
Atrazine is a potent endocrine disruptor that both chemically castrates and feminizes male amphibians. It depletes androgens in adult frogs and reduces androgen-dependent growth of the larynx in developing male larvae.
Collins, Atif, HAYES, Tyrone, Johnston, Gwynne, Kpodzo, Dzifa, Liu, Roger, Mendoza, Magdalena, Noriega, Nigel, Stuart, A, Vonk, Aaron   +8 more
core   +2 more sources