Results 181 to 190 of about 319,930 (224)

Mechanism of catechol estrogen formation in man

Steroids, 1973
Abstract Following the administration of estrone- 3 H-sulfate- 35 S to man, estrone sulfate, 2-methoxyestrone sulfate and 2-hydroxyestrone-2-sulfate were isolated from urine and purified. Their isotope content showed that estrone sulfate and 2-methoxyestrone sulfate retained 23 and 21% of the originally present 35 S, while 2-hydroxyestrone estrone ...
J, Fishman, I, Yoshizawa, L, Hellman
openaire   +2 more sources

Convenient large scale preparation of catechol estrogens

Steroids, 1976
2-Hydroxyestrone, 2-hydroxyestradiol-17beta, 2-hydroxy-17alpha-ethynylestradiol, 2-hydroxyestriol, 4-hydroxyestrone, 4-hydroxyestradiol-17beta, 4-hydroxy-17alpha-ethynylestradiol and 4-hydroxyestriol are prepared on a preparative scale from the corresponding aminophenols using a new inverse oxidation procedure.
G, Stubenrauch, R, Knuppen
openaire   +2 more sources

Cimetidine inhibits catechol estrogen metabolism in women

Maturitas, 1991
Chronic cimetidine use in men is associated with hyperestrogenic side effects such as gynecomastia, which may be linked to inhibition of estradiol 2-hydroxylation. As this property of the drug might be helpful in hypoestrogenic states such as osteoporosis, we investigated the effect of cimetidine on estradiol metabolism in premenopausal and ...
J J, Michnovicz, R A, Galbraith
openaire   +2 more sources

Gas chromatography/mass spectrometry of catechol estrogens

Steroids, 1992
Catecholestrogens (CCEs), namely 2- or 4-hydroxyestradiol and hydroxyestrone, are highly polar, reactive, and extremely labile estrogen metabolites in many experimental conditions. For these reasons, indirect assay methods mainly have been used. Some experimental evidence suggests that CCEs are synthesized and biologically active mostly in target cells.
L A, Castagnetta, O M, Granata, F P, Arcuri, L M, Polito, F, Rosati, G P, Cartoni   +5 more
openaire   +2 more sources

Regioselective reaction of thiols with catechol estrogens and estrogen-O-quinones

Journal of Steroid Biochemistry, 1986
Incubations of [3H]estradiol and [3H]2-hydroxyestradiol (2-OHE2) with rat liver microsomes and mushroom tyrosinase were carried out in the presence of glutathione and 2-mercaptoethanol. A ratio of about 3.5:1 for the C-4 and C-1 thioether conjugates of 2-OHE2 was observed.
Y J, Abul-Hajj, P L, Cisek
openaire   +2 more sources

Interactions between estrogens and catechol amines. 3. Studies on the methylation of catechol estrogens, catechol amines and other catechols by the ctechol-O-methyltransferases of human liver.

Journal of Clinical Endocrinology and Metabolism, 1972
P. Ball, R. Knuppen, M. Haupt, H. Breuer
semanticscholar   +1 more source

[Catechol estrogens].

Nihon rinsho. Japanese journal of clinical medicine, 1985
S, Takagi, M, Saito
openaire   +3 more sources

Catechol estrogens induce proliferation and malignant transformation in prostate epithelial cells.

Toxicology Letters, 2013
H. Mosli, M. Tolba, A. M. Al-Abd, A. Abdel-Naim   +3 more
semanticscholar   +1 more source

The Catechol Estrogens

Neuroendocrinology, 1976
openaire   +2 more sources

Quantitation of catechol estrogens and their N-acetylcysteine conjugates in urine of rats and hamsters.

Chemical Research in Toxicology, 2000
M. Nakagomi, E. Suzuki
semanticscholar   +1 more source