Results 161 to 170 of about 4,921 (204)
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The Journal of Clinical Endocrinology & Metabolism, 1972
The substrate specificity of the catechol-O-methyltransferase, purified from human liver 380-fold, has been tested with a variety of compounds. Catechol estrogens, as well as catechol amines are methylated to their corresponding monomethyl ethers. The relation of the rates of methylation of catechol estrogens and catechol amines depended on enzyme and ...
PETER BALL +3 more
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The substrate specificity of the catechol-O-methyltransferase, purified from human liver 380-fold, has been tested with a variety of compounds. Catechol estrogens, as well as catechol amines are methylated to their corresponding monomethyl ethers. The relation of the rates of methylation of catechol estrogens and catechol amines depended on enzyme and ...
PETER BALL +3 more
openaire +1 more source
Synthesis of N-acetylcysteine conjugates of catechol estrogens
Steroids, 1996The synthesis of N-acetylcysteine conjugates of 2-hydroxyestrone (2-OHE1) and 4-hydroxyestrone (4-OHE1) is described. The reaction of estrone 2,3-quinone with N-acetylcysteine provided 2-OHE1 and its C-4 and C-1 thioether conjugates in a ratio of 1:1, while estrone 3,4-quinone with N-acetylcysteine gave 4-OHE1 and its C-2 thioether conjugate as a sole ...
E, Suzuki +4 more
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Catechol Estrogen Analogs as Probes of Estrogen Carcinogenesis
1996The roles of estrogens in biochemical events leading to tumor formation remain to be fully elucidated. Induction of renal tumors in the estrogen-treated Syrian hamster offers a unique model to study. Catechol estrogen analogs have recently been prepared to examine the effects of A-ring substituents on estrogen metabolism and on estrogeninduced ...
Robert W. Brueggemeier +4 more
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Gas chromatography — mass spectrometry of catechol estrogens
Steroids, 1974Abstract The gas chromatographic and mass spectrometric properties of 19 catechol estrogens and catechol estrogen methyl ethers are reported. The gas chromatographic behaviour of the TMS-derivatives on the stationary phases OV-1, OV-3, OV-7, and OV-17 is examined and correlated with their molecular weight, shape, and polarity. The characteristic mass
H O, Hoppen, L, Siekmann
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Synthesis of catechol estrogens by human uterus and leiomyoma
Steroids, 1981Homogenates of human endometrial, myometrial and leiomyoma tissues were incubated with (2,4,6,7-3H)-estradiol and tritiated catechol estrogens were isolated and identified. Though 2- and 4-hydroxylations were about the same in endometrium, 4-hydroxylation was two to four fold higher than 2-hydroxylation in myometrium and leiomyoma. However, endometrium
V V, Reddy, P, Hanjani, R, Rajan
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A simple chemical method for the synthesis of catechol estrogens
Steroids, 1973Abstract The preparation of 2-hydroxyestrone, 2-hydroxyestradiol-17, 4-hydroxyestrone and 4-hydroxyestradiol-17β by a simple one-step chemical reaction, treatment with potassium nitrosodisulfonate, is described. The structures of the products were established by nmr, ultraviolet, infrared and mass spectra as well as from their chemical and ...
H P, Gelbke, O, Haupt, R, Knuppen
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Nihon rinsho. Japanese journal of clinical medicine, 1985
S, Takagi, M, Saito
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S, Takagi, M, Saito
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Selective sensing of catechol based on a fluorescent nanozyme with catechol oxidase activity
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2023Yongxin Li
exaly