Results 71 to 80 of about 319,930 (224)
Advanced Science, Volume 12, Issue 39, October 20, 2025.This schematic representation illustrates the interaction mechanisms between polyphenolic compounds and various materials (metals, proteins, polysaccharides, alkaloids, etc.). And explains the potential clinical application value of these materials (nanoparticles, coatings, films, capsules, and hydrogels constructed using polyphenols) in the fields of ...
Songwen Xue +6 more
wiley +1 more source
Direct inhibition of tyrosine hydroxylase activity by catechol estrogens.
Journal of Biological Chemistry, 1978 Catechol estrogens, the 2-hydroxylated metabolites of estrogens, recently shown to be formed in brain, inhibit tyrosine hydroxylase, the enzyme that catalyzes the pivotal step in the biosynthesis of the neurotransmitters dopamine and norepinephrine.
T. Lloyd, J. Weisz
semanticscholar +1 more source
Brain and Behavior, Volume 15, Issue 10, October 2025.To systematize the genetic basis correctly associated with nonresponse to triptan, we revised etiological studies on Web of Science, Embase, and PubMed until 2023. We found that only polymorphisms in the SLC6A4, 5‐HT1B, and COMT genes have a stronger association with this condition. More robust studies are needed to increase this certainty.
Victoria Gomes Andreata +14 more
wiley +1 more source
UDP-glucuronosyltransferases in sickness and health : Studies on bilirubin and steroid glucuronidation [PDF]
, 2013 UDP-glucuronosyltransferases (UGTs) are responsible for the metabolism of many xenobiotics, as well as several endogenous compounds like bilirubin and certain steroids.
Sneitz, Nina
core
Dual role of estrogens in endometrial cancer
Zdravniški Vestnik, 2014 Increased local concentrations of estrogens are a well-known risk factor for endometrial cancer. Estrogens can act as mitogens via the estrogen receptors, and by forming oxidative metabolites they can act as cancer initiators.
Neli Hevir Kene, Tea Lanišnik Rižner
doaj
Journal of Biological Chemistry, 1989 Electron spin resonance spectroscopy has been used to detect, characterize, and to infer structures of o-semiquinones derived from stilbene catechol estrogens.
B. Kalyanaraman, R. Sealy, J. Liehr
semanticscholar +1 more source
Cardiovascular autonomic dysfunction and oxidative stress induced by fructose overload in an experimental model of hypertension and menopause [PDF]
, 2014 Background: Metabolic syndrome is characterized by the association of 3 or more risk factors, including: abdominal obesity associated with an excess of abdominal fat, insulin resistance, type 2 diabetes, dyslipidemia and hypertension.
Bernardes, Nathalia +8 more
core +2 more sources
Effect of Tumour Necrosis Factor-Alpha on Estrogen Metabolic Pathways in Breast Cancer Cells
Journal of Cancer, 2012 Tumor necrosis factor-alpha (TNF-α) is a proinflammatory cytokine that has been linked to breast cancer development. Estrogen metabolic pathway is also involved in breast carcinogenesis and DNA adducts formation.
Marwa Kamel, Samia Shouman, Mahmoud El-Merzebany, Gokhan Kilic, Timothy Veenstra, Muhammad Saeed, Mohamed Wagih, Concepcion Diaz-Arrastia, Deepa Patel, Salama Salama
doaj
ESR identification of free radicals formed from the oxidation of catechol estrogens by Cu2+.
Archives of Biochemistry and Biophysics, 1997 Catechol estrogens are genotoxic, indirectly through redox cycling mechanisms leading to oxidative DNA damage and directly by formation of quinone-DNA adducts.
A. Seacat +3 more
semanticscholar +1 more source
Environmental Pollutant Hexachlorobenzene Induces Hypertension In a Rat Model [PDF]
, 2018 Hexachlorobenzene (HCB) is a dioxin-like environmental pollutant, widely distributed in the environment. New research links exposure to high levels of persistent organic environmental toxicants to cardiovascular disease, however little is known about the
Alvarez, Laura +8 more
core +1 more source