Effect of Tumour Necrosis Factor-Alpha on Estrogen Metabolic Pathways in Breast Cancer Cells
Journal of Cancer, 2012 Tumor necrosis factor-alpha (TNF-α) is a proinflammatory cytokine that has been linked to breast cancer development. Estrogen metabolic pathway is also involved in breast carcinogenesis and DNA adducts formation.
Marwa Kamel, Samia Shouman, Mahmoud El-Merzebany, Gokhan Kilic, Timothy Veenstra, Muhammad Saeed, Mohamed Wagih, Concepcion Diaz-Arrastia, Deepa Patel, Salama Salama
doaj
Association of COMT genotypes with S-COMT promoter methylation in growth-discordant monozygotic twins and healthy adults [PDF]
, 2011 Background Catechol-O-Methyltransferase (COMT) plays a key role in dopamine and estrogen metabolism. Recently, COMT haplotypes rather than the single polymorphism Val158Met have been reported to underlie differences in protein expression by modulating ...
Bartmann, Peter +9 more
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Sex hormones and hypertension [PDF]
, 2017 Gender has an important influence on blood pressure, with premenopausal women having a lower arterial blood pressure than age-matched men. Compared with premenopausal women, postmenopausal women have higher blood pressures, suggesting that ovarian ...
Dubey, Raghvendra K. +3 more
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Enantiomers of methylenedioxy designer drugs : the role of cytochrome P450s and catechol-O-methyltransferase in their metabolism [PDF]
, 2009 In the presented studies, the CYP dependent, enantioselective N-dealkylation and demethylenation of the designer drugs MDMA (Ecstasy), MBDB (Eden), and MDEA (Eve) was investigated.
Meyer, Markus Robert
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Importance of xeroderma pigmentosum group D polymorphisms in susceptibility to ovarian cancer [PDF]
, 2007 The purpose of this study was to evaluate the role of XPD genotypes as genetic indicator of susceptibility to ovarian cancer. We have used a case–control study.
Costa, Sandra Maria Araújo da +7 more
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Catechol estrogens as biomarkers for mammary gland cancer
International Journal of Oncology, 2011 The origin of human tumors has been attributed to the exposure to several environmental chemicals and implicated in the increase of incidence in breast cancer. Progression of breast cancer follows a complex multistep process that seems to depend on various exogenous and endogenous factors.
Calaf, Gloria M., Garrido, Fernando
openaire +5 more sources
Dibenzo[a,g]quinolizin-8-ones: synthesis, estrogen receptor affinities, and cytostatic activity [PDF]
, 1992 A number of acetoxy-substituted dibenzo[a,g]quinolizin-8-ones were synthesized by the reaction of 1-oxoisoquinolines with substituted homophthalic acid anhydride.
Angerer, S. von +4 more
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UDP-glucuronosyltransferases in sickness and health : Studies on bilirubin and steroid glucuronidation [PDF]
, 2013 UDP-glucuronosyltransferases (UGTs) are responsible for the metabolism of many xenobiotics, as well as several endogenous compounds like bilirubin and certain steroids.
Sneitz, Nina
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Oncometabolites as biomarkers in thyroid cancer: a systematic review
Cancer Management and Research, 2019 Fatemeh Khatami,1 Moloud Payab,2 Masoumeh Sarvari,3 Kambiz Gilany,3–5 Bagher Larijani,6 Babak Arjmand,7 Seyed Mohammad Tavangar1,8 1Chronic Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of ...
Khatami F +6 more
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Mecanismos envolvidos no câncer de mama porconsumo de álcool e alternativas para sua prevenção [PDF]
, 2015 El consumo de alcohol se asocia con un riesgo incrementado para el cáncer de mama, aumentando linealmente incluso con un consumo moderado y con independencia del tipo de bebida alcohólica. El mecanismo está aún lejos de haberse establecido.
Castro, Gerardo Daniel +3 more
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