Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Endogenous hypercortisolism (EHC) is an underrecognised and clinically significant contributor to hypertension, particularly resistant hypertension. Once viewed as a rare entity, EHC is now understood as a spectrum of cortisol excess associated with adverse cardiometabolic outcomes and target‐organ damage.
Omar Al Dhaybi, Deepak L. Bhatt
wiley +1 more source
Transdermal Hormonal Therapy in Menopause: Current Evidence and Personalized Approaches. [PDF]
PharmaceuticsMihai MM +9 more
europepmc +1 more source
Hypercortisolism: An Under‐Recognised Pathway Linked to Multi‐System Complications
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT The clinical understanding of hypercortisolism (HC) has evolved from a classic overt syndrome with florid Cushingoid features to a broader spectrum of disease that includes milder presentations, often referred to as mild autonomous cortisol secretion (MACS).
Hernan Daniel Sacoto, Vivian A. Fonseca
wiley +1 more source
Biological and computer-aided evaluation of 3-methoxy-13α-estrone-16α-diphenylphosphine oxide as a new antiestrogenic agent. [PDF]
Sci RepBartha S +8 more
europepmc +1 more source
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aim To provide a practical guide on when to suspect endogenous hypercortisolism, how to use the overnight 1‐mg dexamethasone suppression test (DST) for targeted case‐finding, and which patients are most likely to benefit from treatment.
Juan Pablo Frias
wiley +1 more source
Telitacicept versus belimumab for the treatment of systemic lupus erythematosus: a network meta-analysis and cost-effectiveness analysis. [PDF]
Lupus Sci MedDeng L +6 more
europepmc +1 more source
From hepatic to hematopoietic: LRH‐1's expanding cellular repertoire to the immune system
The FEBS Journal, EarlyView.The nuclear receptor LRH‐1 is a well‐characterized regulator of endodermal tissue. Yet, increasing evidence indicates that LRH‐1, although expressed at low levels, is also a critical regulator of the hematopoietic system. LRH‐1 regulates the immune system by contributing to immune cell‐specific functions.
Lukas Meisinger +3 more
wiley +1 more source
Estren prevents beta-amyloid-induced basal forebrain cholinergic loss and long-term spatial memory deficits in aged female mice. [PDF]
Sci RepMcLoughlin J +10 more
europepmc +1 more source
Breast cancer-related endocrine therapy on ocular surface microbiota: mechanism and clinical significance. [PDF]
Int J OphthalmolYuan C, Hu XC, Tan RX, Liu C.
europepmc +1 more source
The Impact of Hidradenitis Suppurativa on Sexual Function: A Multicentered Cross‐Sectional Study
International Journal of Dermatology, EarlyView.Summary of a multicenter study of 522 patients with hidradenitis suppurativa (HS) evaluating quality of life, disease severity, and sexual function. HS was associated with impaired sexual function in both women and men, with pain identified as a central driver.
Defne Özkoca +24 more
wiley +1 more source