Results 91 to 100 of about 5,290 (236)

Sleep Disorders in Klinefelter Syndrome and Other Sex Chromosome Aneuploidies: A Narrative Review

Andrology, EarlyView.
ABSTRACT Background Sex chromosome aneuploidies (SCAs) are among the most frequent types of chromosomal aneuploidies and include Klinefelter syndrome (47,XXY and higher‐grade variants), 47,XYY syndrome, Turner syndrome (45,X), and trisomy X (47,XXX).
Roberto Paparella, Fabiola Panvino, Ida Pucarelli, Luigi Tarani   +3 more
wiley   +1 more source

Estrone-α-2-Deoxy-Glucoside as a Targeted Therapy for Triple-Negative Breast Cancer: Aromatase Inhibition and Cytotoxicity. [PDF]

Chem Biol Drug Des
Huang TY, Wang MR, Chou FP, Huang SC, Hsiao PY, Wu TK.   +5 more
europepmc   +1 more source

The Bidirectional Association Between MASLD and Male Hypogonadism: An Updated Meta‐Analysis

Andrology, EarlyView.
ABSTRACT Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) and male hypogonadism are increasingly prevalent, metabolically interrelated conditions. Testosterone (T) deficiency has been implicated in hepatic lipid dysregulation, insulin resistance, and visceral adiposity, whereas MASLD may impair the hypothalamic–pituitary ...
Giorgia Spaggiari, Leonardo Dalla Valentina, Cristina Felicani, Filippo Gabrielli, Simonetta Lugari, Giovanni Corona, Paolo Ventura, Manuela Simoni, Fabio Nascimbeni, Daniele Santi   +9 more
wiley   +1 more source

The letrozole use in reproductive medicine: Beyond aromatase inhibition - a comprehensive review. [PDF]

Turk J Obstet Gynecol
Aydın G, Hatırnaz Ş, Saynur Hatırnaz E, Çetinkaya MB, Akdeniz M, Dokuzeylül Güngör N, Güler O, Merdanoğlu MA, Uzun A, Eroğlu S, Tosun Ö, Bahadırlı A, Yurtçu E, Keyif B, Güvey H, Gürkan N, Karlı P, Yılmaz Z, Baldini GM, Tavuz Aİ, Sparic R, Tabakova N, Tinelli A, Cao M, Ta SL, Hatırnaz O, Dahan M.   +26 more
europepmc   +1 more source

Sex Steroids Measurement by Mass Spectrometry in Hypogonadal Men in a Real‐World Setting: Serum Estradiol (E2) and E2 to Total Testosterone Ratio Do Not Differ Between Patients With Klinefelter Syndrome and Non‐Klinefelter Syndrome Hypogonadism

Andrology, EarlyView.
ABSTRACT Background Traditionally, Klinefelter syndrome (KS) was considered a clinical condition associated with hyperestrogenism. Aim To compare circulating sex steroids, particularly estrogens, in a cohort of KS and non‐KS hypogonadal men. Materials and Methods A cohort of hypogonadal men, treated and untreated, was prospectively enrolled in a real ...
Daniele Renda Livraghi, Francesco Costantino, Filippo Vignali, Giulia Canu, Maria Cristina De Santis, Laura Roli, Tommaso Fasano, Vincenzo Rochira, Sara De Vincentis   +8 more
wiley   +1 more source

Estrogenic activity of mixtures in the Salish Sea: The use of high throughput toxicity data with chemical information from fish bile and other matrices. [PDF]

PLoS One
Faber M, James CA, Harding LB, da Silva DAM, Sofield RM.   +4 more
europepmc   +1 more source

Bone Health and Aging in Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Klinefelter syndrome (KS) is typically diagnosed in young adults, but advances in prenatal testing have led to its recognition at a much earlier age. Conversely, diagnosis in late adulthood remains uncommon, but still occurs. Independently from the age at diagnosis, KS individuals now receive more accurate and tailored care management than in ...
Filippo Vignali, Daniele Renda Livraghi, Francesco Costantino, Sara De Vincentis, Vincenzo Rochira   +4 more
wiley   +1 more source

Plaque-Type Psoriasis Induced by Non-Steroidal Aromatase Inhibitor (Letrozole): A Case Series. [PDF]

Cureus
Alkaltham GK, Almulhim AN, Shaikh LY, Alsebayel M.   +3 more
europepmc   +1 more source

Gold‐standard evidence and best practice guidance for menstrual cycle‐informed clinical care: An overview for clinicians

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives To synthesize current evidence and provide clinically actionable recommendations for integrating menstrual cycle‐related processes—particularly hormone sensitivity, Premenstrual Dysphoric Disorder (PMDD) and Premenstrual Exacerbation (PME)—into psychological assessment, formulation and treatment.
Ellen R. Lambert, Louise N. Nolan, Katja M. Schmalenberger   +2 more
wiley   +1 more source

Targeting Steroid-Metabolizing Enzymes with 15β-Substituted Estrone Analogues: Dual Discovery of AKR1C2/17β-HSD1 Inhibitors and a Fluorescent 17β-HSD1 Ligand. [PDF]

Cancers (Basel)
Resch V, Gjorgoska M, Hafner E, Bacsa I, Kovács B, Büdefeld T, Hunyadi A, Huliák I, Kiricsi M, Paragi G, Rižner TL, Mernyák E.   +11 more
europepmc   +1 more source