Results 81 to 90 of about 5,290 (236)

Palbociclib in the Treatment of HR+/ HER2‐ Advanced or Metastatic Breast Cancer in Australia: A Real‐World Retrospective Analysis

Asia-Pacific Journal of Clinical Oncology, EarlyView.
This study investigated the real‐world use of CDK4/6 inhibitors in Australian patients with HR+/HER2‐ advanced or metastatic breast cancer, providing data on patient demographics, treatment patterns, and outcomes with palbociclib. ABSTRACT Background There is limited real‐world data on the use of CDK4/6 inhibitors in Australian patients with HR+/HER2 ...
Louise Nott, Eugene Moylan, Maree Colosimo, Giles Stratton, Thomas Chiu, Mahsa H. Kouhkamari, Maureen Hitschfeld, Jessica Michie, Richard De Boer   +8 more
wiley   +1 more source

Exploring the Health Effects of Phytoestrogens. [PDF]

Metabolites
Kraus V, Birková A, Majerníková M, Čižmárová B.   +3 more
europepmc   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Estrogen associations with human pregnancy related increases in cytochrome P450 3A activity. [PDF]

Front Pharmacol
Fashe MM, Lee J, Grieco JT, Fallon JK, Mulrenin IR, Gower MN, Jackson KD, Boggess KA, Lee CR.   +8 more
europepmc   +1 more source

Postcode‐Level Variation and Environmental Determinants of Respiratory Allergies in a Large German Cohort

Allergy, EarlyView.
Young children (0–9 years) and residents of urban areas appeared particularly vulnerable to respiratory allergy development and exacerbation. Incidence showed nonlinear associations with PM10, PM2.5, temperature, and alder/birch pollen, while DPMR showed similar patterns, except for NO2 and the interaction O3*NO2.
Trang Dao‐Siebel, Christoph Knote, Christoph Müller, Thilo Erbertseder, Elke Hertig, Roxana Halbleib, Evelyn Lamy   +6 more
wiley   +1 more source

Environmental estrogens and animal reproductive health: mechanisms, biomarkers, and intervention approaches. [PDF]

J Anim Sci Biotechnol
Liang S, Ma J, Chen S, Dong X, Lu J, Zhu Y, Chen L, Wang Y, Niu L, Zhao Y, Shen L, Zhu L, Gan M.   +12 more
europepmc   +1 more source

Addressing inequities in the design and delivery of prehabilitation in the UK: case studies of challenges, complexities and good practice*

Anaesthesia, EarlyView.
Summary Introduction Prehabilitation has become increasingly prominent in the context of cancer surgery. While prehabilitation offers significant benefits, it can also inadvertently broaden inequalities because it is often more accessible to some than others.
Charlotte Hadley, Xiubin Zhang, Hilary Stewart, Sophie Stanley, Ces Kulikowski, Andrea Partridge, Laura Wareing, Lisa Ashmore, Christopher Gaffney, Jo Rycroft Malone, Andrew Smith, Cliff Shelton   +11 more
wiley   +1 more source

Green and Emerging Microextraction Strategies for Bioanalytical Determination of Hormones: Trends, Challenges, and Applications. [PDF]

Molecules
Vicente-Zurdo D, Morante-Zarcero S, Sierra I.   +2 more
europepmc   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

Andrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos, Marie‐Pier Scott‐Boyer, Arnaud Droit, Robert S. Viger, Jacques J. Tremblay   +4 more
wiley   +1 more source

Steroid-Induced Thrombosis: A Comprehensive Analysis Using the FAERS Database. [PDF]

Pharmaceuticals (Basel)
Watanabe A, Uesawa Y.
europepmc   +1 more source