Results 11 to 20 of about 7,787 (278)

Non-Steroidal Estrogens Inhibit Influenza Virus by Interacting with Hemagglutinin and Preventing Viral Fusion

open access: yesInternational Journal of Molecular Sciences, 2023
Influenza virus is one of the main causes of respiratory infections worldwide. Despite the availability of seasonal vaccines and antivirals, influenza virus infections cause an important health and economic burden. Therefore, the need to identify alternative antiviral strategies persists.
Franzi, Elisa   +7 more
openaire   +4 more sources

The fate of steroid estrogens: Partitioning during wastewater treatment and onto river sediments [PDF]

open access: yes, 2010
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2010 Springer Science+Business Media B.V.The partitioning of steroid estrogens in wastewater treatment and receiving waters is likely to ...
Scrimshaw, Mark D.   +11 more
core   +1 more source

Structure–activity studies of non-steroid analogues structurally-related to neuroprotective estrogens [PDF]

open access: yesOrganic & Biomolecular Chemistry, 2016
Estrone and 17β-estradiol are phenolic steroids that are known to be neuroprotective in multiple models of neuronal injury.
Mingxing, Qian   +5 more
openaire   +2 more sources

Selenophenes: Introducing a New Element into the Core of Non‐Steroidal Estrogen Receptor Ligands [PDF]

open access: yesChemMedChem, 2017
AbstractThe importance of the heterocyclic core elements with peripheral phenolic and alkyl substituents as a dominant structural motif of ligands for the estrogen receptor (ER) has been well recognized. In this study we expanded the structural diversity of core elements by preparing selenium‐containing heterocycles and exploring the activities of ...
Silong, Zhang   +10 more
openaire   +2 more sources

Drug-induced liver injury after switching from tamoxifen to anastrozole in a patient with a history of breast cancer being treated for hypertension and diabetes

open access: yesTherapeutic Advances in Chronic Disease, 2020
Anastrozole is a selective non-steroidal aromatase inhibitor that blocks the conversion of androgens to estrogens in peripheral tissues. It is used as adjuvant therapy for early-stage hormone-sensitive breast cancer in postmenopausal women.
Petr Potmešil, Radka Szotkowská
doaj   +1 more source

Detection of xenoestrogens in serum after immunoprecipitation of endogenous steroidal estrogens. [PDF]

open access: yes, 2002
In this article we report a simple and efficient method for detecting nonsteroidal estrogens in a biologic sample. This method uses polyclonal antibodies to estradiol (E2) to immunoprecipitate these major biologically active steroidal estrogens, leaving ...
Lasley, Bill L   +15 more
core   +1 more source

Mechanisms, Cofactors, and Augmenting Factors Involved in Anaphylaxis

open access: yesFrontiers in Immunology, 2017
Anaphylaxis is an acute and life-threatening systemic reaction. Many triggers have been described, including food, drug, and hymenoptera allergens, which are the most frequently involved. The mechanisms described in anaphylactic reactions are complex and
Rosa Muñoz-Cano   +12 more
doaj   +1 more source

Screening and risk management solutions for steroidal estrogens in surface and wastewater [PDF]

open access: yes, 2018
Background: The European Commission Implementing Decision EU 2015/495 included three steroidal estrogens, namely 17α-ethinyl estradiol, 17β-estradiol, and estrone, in the so-called “watch list” of the EU Water Framework Directive (WFD). The monitoring of
Marneffe Y.   +35 more
core   +2 more sources

Ensaio clínico placebo-controlado com isoflavonas da soja para sintomas depressivos em mulheres no climatério Placebo-controlled clinical trial with soy isoflavones for depressive symptoms in climacteric women

open access: yesRevista Brasileira de Ginecologia e Obstetrícia, 2006
OBJETIVOS: avaliar a eficácia do uso de isoflavonas da soja no tratamento de sintomas depressivos em mulheres com síndrome climatérica. MÉTODOS: estudo experimental placebo-controlado, randomizado e duplo-cego, com 84 pacientes climatéricas atendidas ...
Rilva Lopes de Sousa   +4 more
doaj   +1 more source

Inhibition of Human Phenol and Estrogen Sulfotransferase by Certain Non-Steroidal Anti-Inflammatory Agents [PDF]

open access: yesCurrent Drug Metabolism, 2006
We hypothesized that aryl acetate- and aryl carboxylate-containing drugs would inhibit human phenol sulfotransferase (SULT1A1), and that selectivity would depend upon the interaction of the aryl portion of the molecule with the sulfotransferase acceptor binding site. This hypothesis was based on results with the rat orthologue showing that oxidation of
King, Roberta S., Ghosh, A., Wu, Jinfang
openaire   +3 more sources

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