Results 191 to 200 of about 12,973 (282)

Steroid hormones in fish, caution for present and future: A review. [PDF]

Toxicol Rep
Islam P, Hossain MI, Khatun P, Masud RI, Tasnim S, Anjum M, Islam MZ, Nibir SS, Rafiq K, Islam MA.   +9 more
europepmc   +1 more source

From “Passive Supplementation” to “Active Repair”: Melatonin Reshapes the Treatment Paradigm for Late‐Onset Hypogonadism by Targeting Leydig Cell Senescence

Aging Cell, Volume 25, Issue 5, May 2026.
Melatonin restores testosterone production in aging Leydig cells by targeting key pathological drivers, particularly oxidative stress and mitochondrial dysfunction. This approach offers a fundamental strategy to reshape the Late‐onset hypogonadism treatment paradigm.
Hui Wu, Gang Ning, Mintao Jian, Ajian Peng, Haoyu Wang, Bonan Li, Xing Zhou   +6 more
wiley   +1 more source

Bicalutamide: A review. [PDF]

J Cutan Aesthet Surg
Aulakh S, Mysore V.
europepmc   +1 more source

Fasting and Caloric Restriction Activate an ADIOL‐NHR‐91‐Kynurenine Pathway Signaling Axis to Promote Healthspan

Aging Cell, Volume 25, Issue 5, May 2026.
The steroid hormone ADIOL emerges as a key mediator of fasting–and caloric restriction–induced healthspan benefits in C. elegans. These regimens activate ADIOL production, which acts through the estrogen receptor β homolog NHR‐91 to reduce neural kynurenic acid levels and enhance healthspan independently of lifespan. ADIOL supplementation, even late in
Ana Guijarro‐Hernández, Shinja Yoo, George A. Lemieux, Sena Komatsu, Abdullah Q. Latiff, Rishika R. Patil, Kaveh Ashrafi   +6 more
wiley   +1 more source

New Promising Steroidal Aromatase Inhibitors with Multi-Target Action on Estrogen and Androgen Receptors for Breast Cancer Treatment. [PDF]

Cancers (Basel)
Amaral C, Almeida CF, Valente MJ, Varela CL, Costa SC, Roleira FMF, Tavares-da-Silva E, Vinggaard AM, Teixeira N, Correia-da-Silva G.   +9 more
europepmc   +1 more source

Age‐Dependent Alterations of Chromosomal Passenger Complex Members During Implantation and Decidualization in the Mouse Uterus

Aging Cell, Volume 25, Issue 5, May 2026.
Aging in females reduces the number of implantation sites and leads to specific, compartment‐dependent changes in components of the chromosomal passenger complex (pIncenp, Aurora B, Survivin, Borealin) during mouse uterine implantation and decidualization.
Ezgi Golal, Cemre Nur Balci, Nuray Acar
wiley   +1 more source

Medical Treatment for Endometriosis: One Size Does Not Fit All. [PDF]

J Clin Med
Vercellini P, Salmeri N, Bandini V, Conca B, Viganò P, Somigliana E, Vignali M.   +6 more
europepmc   +1 more source

Beyond the Barrier: Epithelial Cells as Immune Sentinels in the Female Genital Tract

American Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.
ABSTRACT Epithelial cells (ECs) of the female genital tract (FGT) serve as an essential barrier and the first line of defense against sexually transmitted pathogens. Beyond providing a physical barrier, these cells actively contribute to immune responses through pathogen recognition, cytokine release, and modulation of adaptive immune responses ...
Lauren Jirik, Shreya Joshi, Aisha Nazli, Charu Kaushic   +3 more
wiley   +1 more source

Bone Effects of Anti-Cancer Treatments in 2024. [PDF]

Calcif Tissue Int
Teissonnière M, Point M, Biver E, Hadji P, Bonnelye E, Ebeling PR, Kendler D, de Villiers T, Holzer G, Body JJ, Fuleihan GEH, Brandi ML, Rizzoli R, Confavreux CB.   +13 more
europepmc   +1 more source

Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders

Andrology, Volume 14, Issue 4, Page 1002-1016, May 2026.
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret, Aaran H. Patel, Elisabeth Daniels, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source