Results 201 to 210 of about 7,787 (278)
Genomic Analysis of Inbreeding Depression on Productive Traits in Rubia Galega Beef Cattle Breed
ABSTRACT In autochthonous livestock breeds with small populations, such as the Rubia Galega from Galicia (Spain), mating between relatives is common and can lead to inbreeding depression. Genomic inbreeding coefficients were estimated for 4984 animals using ~63,000 SNPs to assess inbreeding depression in four key traits: age at first calving (AFC) with
N. Mejuto‐Vázquez +6 more
wiley +1 more source
Machine Learning Accelerates Crystallization for Structure Determination
Single‐crystal X‐ray diffraction (SCXRD) is often constrained by the difficulty of obtaining suitable crystals. Here, a machine learning‐accelerated co‐crystal discovery workflow is established for a crystalline mate strategy that achieves over 95% prediction accuracy and experimentally delivers 114 co‐crystals from 120 candidates.
Cui‐Zhou Luan +10 more
wiley +2 more sources
Steroid hormones in fish, caution for present and future: A review. [PDF]
Islam P +9 more
europepmc +1 more source
ABSTRACT Accurate inference of sexual maturity is fundamental to interpreting marine mammal life histories and population structure. Using Bayesian logistic regression models with a hierarchical ordinal (HOF‐style) parameterisation and canonical analysis of principal coordinates (CAP), we evaluate skeletal metrics in the pectoral flippers of common ...
Eva‐Maria F. Hanninger +8 more
wiley +1 more source
Endometriosis, symptoms, and risk for depression and/or anxiety: a population-based retrospective study. [PDF]
Goodwin E +5 more
europepmc +1 more source
GR‐A knockin mice were generated that express the classic full‐length glucocorticoid receptor (GR‐A) but lack the highly conserved translational isoforms GR‐B, GR‐C1, GR‐C2, GR‐C3, GR‐D1, GR‐D2, and GR‐D3 that have progressively shorter N‐terminal transactivation domains (NTDs).
Robert H. Oakley +8 more
wiley +1 more source
New Promising Steroidal Aromatase Inhibitors with Multi-Target Action on Estrogen and Androgen Receptors for Breast Cancer Treatment. [PDF]
Amaral C +9 more
europepmc +1 more source
Bone Effects of Anti-Cancer Treatments in 2024. [PDF]
Teissonnière M +13 more
europepmc +1 more source
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner +14 more
wiley +1 more source

