Results 91 to 100 of about 484,096 (391)
Dermato-Endocrinology, 2013 Estrogen deficiency following menopause results in atrophic skin changes and acceleration of skin aging. Estrogens significantly modulate skin physiology, targeting keratinocytes, fibroblasts, melanocytes, hair follicles and sebaceous glands, and improve
M. Thornton
semanticscholar +1 more source
Advanced Biology, EarlyView.This study introduces and investigates different‐sex gonad transplants in a mouse model of gender‐affirming hormone therapy. Ovaries and testes implanted into gonadectomized adults exhibit gametogenesis and steroidogenesis independent of the sex of the host.
Daniel R. Pfau +8 more
wiley +1 more source
Estrogens regulate the hepatic effects of Growth Hormone, a hormonal interplay with multiple fates
Frontiers in Endocrinology, 2013 The liver responds to estrogens and GH which are critical regulators of body growth, gender-related hepatic functions, and intermediate metabolism. The effects of estrogens on liver can be direct, through the direct actions of hepatic ER, or indirect ...
Leandro eFernandez-Perez +3 more
doaj +1 more source
Breast Cancer Research, 2022 Background Several anthropometric measures have been associated with hormone-related cancers, and it has been shown that estrogen metabolism in postmenopausal women plays an important role in these relationships.
Ashley M. Geczik +23 more
doaj +1 more source
The serotonin transporter promotes a pathological estrogen metabolic pathway in pulmonary hypertension via cytochrome P450 1B1 pulmonary circulation [PDF]
, 2016 Pulmonary arterial hypertension (PAH) is a devastating vasculopathy that predominates in women and has been associated with dysregulated estrogen and serotonin signaling. Overexpression of the serotonin transporter (SERT+) in mice results in an estrogen-
Anagnostopoulou, Aikaterini +9 more
core +1 more source
Repurposing the estrogen receptor modulator raloxifene to treat SARS-CoV-2 infection [PDF]
, 2021 Marcello Allegretti +8 more
openalex +1 more source
Engineering the Link: From Genome Interaction Maps to Functional Insight
Advanced Biology, EarlyView.Advances in chromosome conformation capture have revealed the genome's 3D organization, yet its causal impact on gene regulation remains elusive. This review highlights emerging genome‐engineering tools ‐ zinc fingers, TALEs, and CRISPR‐Cas9 ‐ that enable targeted manipulation of chromatin loops to dissect structure–function relationships. It discusses
Frido Petersen +5 more
wiley +1 more source
Potassium, magnesium and pyridoxine in the context of the biological effects of estrogens [PDF]
Гинекология, 2017 Potassium and magnesium ions are essential for realizing the biological effects of estrogens. Magnesium ions promote the translocation of the estrogen receptors into the nucleus of the cell and regulate the potassium channels that are involved in the ...
O A Gromova +4 more
doaj
Weak if any effect of estrogen on spatial memory in rats [PDF]
, 2002 In a number of species, males appear to have spatial abilities that are superior to those of females. The favored explanation for this cognitive difference is hormonal: higher testosterone levels in males than in females.
Farkas, Tamás +5 more
core
Managing menopausal symptoms and associated clinical issues in breast cancer survivors [PDF]
, 2017 Objective: Review evidence to guide management of menopausal signs and symptoms in women after breast cancer and make recommendations accordingly. Evidence: Randomized controlled clinical trials, observational studies, evidence-based guidelines, and
Davis, Susan R. +5 more
core +1 more source