Results 131 to 140 of about 162,839 (298)

Fecal Elimination of Hormones in Sheep and Cattle Treated with Synthetic Estrogens [PDF]

, 1956
Martin Stob
openalex   +1 more source

Hepatic KLF9 Deficiency Inhibits Dehydroepiandrosterone (DHEA)‐Induced Polycystic Ovary Syndrome via Liver‐Ovary Axis

Advanced Science, EarlyView.
The study shows that liver is a previously unrecognized extraovarian organ that plays a key role about androgen homeostasis in the development of DHEA‐induced PCOS. DHEA is the most common precursor of active androgen, such as DHT, and KLF9 is required for the conversion of DHEA to DHT and hepatic KLF9 might be a potential therapeutic target for PCOS ...
Jianli Song, Zhaoqing Guan, Guiyi Ji, Jing Wang, Xiurui Yan, Yujie Zhang, Yinliang Zhang, Chunfang Ha, Rong Hu, Yongsheng Chang, Yaolin Zhang, Heng Fan   +11 more
wiley   +1 more source

DISTRIBUTIONS OF ESTROGENS BETWEEN IMMISCIBLE SOLVENTS

, 1942
Alan E. Mather
openalex   +1 more source

1, 2-Bis-(p-hydroxyphenyl)-1, 2-bis-(methylthio)-ethane, An Estrogenic Sulfur Analog of Hexestrol [PDF]

, 1950
Yoshiyuki Urushibara, Michinori Ōki
openalex   +1 more source

Allele‐Specific Regulation of PAXIP1‐AS1 by SMC3/CEBPB at rs112651172 in Psychiatric Disorders Drives Synaptic and Behavioral Dysfunctions in Mice

Advanced Science, EarlyView.
This study identifies a functional noncoding variant, rs112651172 (C/G), that drives allele‐specific expression of PAXIP1‐AS1 in monozygotic twin pairs discordant for schizophrenia and bipolar disorder. The risk G allele enhances CEBPB binding, leading to lncRNA upregulation, CNTNAP3 derepression, and synaptic and behavioral deficits in mice.
Chaoying Ni, He Chen, Qiaqi Chen, Yangyang Liao, Yunqian Wang, Linyan Ye, Xiaohui Wu, Hongyu Ni, Tingyun Jiang, Shufen Li, Qiong Yang, Hong Xue, Zhongju Wang, Feng Yi, Cunyou Zhao   +14 more
wiley   +1 more source

STUDIES CONCERNING THE MECHANISM CONTROLLING THE INITIATION OF LACTATION AT PARTURITION III. CAN ESTROGEN ACCOUNT FOR THE PRECIPITOUS INCREASE IN THE LACTOGEN CONTENT OF THE PITUITARY FOLLOWING PARTURITION?¹,²

, 1942
J. Meites, C. W. Turner
openalex   +1 more source

Synergistic Promotion of Triple‐Negative Breast Cancer Tumorigenesis and Metastasis by Oral Polystyrene Nanoplastics Exposure via Alloprevotella‐Derived Glutamate and Platelet Activation

Advanced Science, EarlyView.
Polystyrene nanoplastics (PS‐NPs) administered via oral exposure accelerate triple‐negative breast cancer (TNBC) progression by synergistically modulating gut microbiota‐derived glutamate production and platelet activation. This study uncovers a pivotal crosstalk between microbial metabolites and platelet‐tumor interactions, offering mechanistic ...
Leilei Zhu, Peihao Xu, Mingyuan Zhou, Kewei Li, Shasha Tian, Xuemei Fan, Junling Liu, Baodong Ye, Zhishan Ding, Yingzhi Shen   +9 more
wiley   +1 more source

Diversity of estrogen biodegradation pathways and application in environmental bioremediation. [PDF]

Front Microbiol
Hashem JS, Ismail W, Chiang YR, Bekhit AA.   +3 more
europepmc   +1 more source

Hydrogen‐Deuterium Exchange Mass Spectrometry for Molecular Glue Characterization

Advanced Science, EarlyView.
Molecular glues that stabilize protein–protein interactions are challenging to identify. Here, hydrogen‐deuterium exchange mass spectrometry can show and reveal gluing mechanisms that vary between protein binding partners. Abstract Molecular glues are powerful bioactive molecules that stabilize protein–protein interactions.
Danielle F. Kay, Hadeeqa G. Raza, Richard G. Doveston, Aneika C. Leney   +3 more
wiley   +1 more source

A Systematic Review of Estrogens as Emerging Contaminants in Water: A Global Overview Study from the One Health Perspective. [PDF]

J Xenobiot
da Silva RL, Lima E Silva MA, Teixeira TP, Farnesi de Assunção TS, Teixeira PP, Tamagno WA, Rocha TL, Gonçalves JCSI, Marcon M.   +8 more
europepmc   +1 more source