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Estrogens, estrogen receptors and melanoma
Expert Review of Anticancer Therapy, 2011The skin is the largest nonreproductive target tissue on which estrogen plays many beneficial and protective roles. Although neither exogenous hormones nor pregnancy represent significant risk factors for melanoma, epidemiological data suggest a higher survival rate in women with metastatic disease versus men and in premenopausal versus postmenopausal ...
Vincenzo De Giorgi +8 more
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Obstetrical & Gynecological Survey, 1962
The formation of estrogens and phenolic material from a large number of do Cis, C19 and C2i steroids and related structures has been investigated, employing a human placental microsomal preparation supplemented with TPNH and oxygen. The data from the incubation of 2 C 14-labeled androgens are included.
C, GUAL +4 more
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The formation of estrogens and phenolic material from a large number of do Cis, C19 and C2i steroids and related structures has been investigated, employing a human placental microsomal preparation supplemented with TPNH and oxygen. The data from the incubation of 2 C 14-labeled androgens are included.
C, GUAL +4 more
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The Role of Estrogen and Estrogen Receptors in Chemoresistance
Current Medicinal Chemistry, 2011Drug resistance is one of the major obstacles limiting the success of cancer chemotherapy. Biological mechanisms contributing to drug resistance may be present de novo and related to inherent features or may be raised after exposure to anticancer drugs. In recent years, both clinical observations and experimental studies suggested that steroid hormones
M, Sui, H, Zhang, W, Fan
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Enzymatic treatment of estrogens and estrogen glucuronide
Journal of Environmental Sciences, 2009Natural and synthetic estrogens from sewage treatment systems are suspected to influence the reproductive health of the animals in the rivers. In this article, we investigated the enzymatic treatment of three estrogens (estrone, 17beta-estradiol, and 17alpha-ethynyletstradiol) by a fungal laccase which oxidize phenolic compounds with dissolved oxygen ...
Takaaki, Tanaka +6 more
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Biological Role of Estrogen and Estrogen Receptors
Critical Reviews in Biochemistry and Molecular Biology, 2002(2002). Biological Role of Estrogen and Estrogen Receptors. Critical Reviews in Biochemistry and Molecular Biology: Vol. 37, No. 1, pp. 1-28.
Stefan, Nilsson, Jan-Ake, Gustafsson
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Estrogen and estrogen receptors in thyroid carcinomas
Journal of Surgical Oncology, 1991AbstractThyroid tissues, composed of normal thyroid (10 cases), Graves' thyroid (4), and papillary carcinoma (10), were measured for the presence of receptors for estrogen (ER) using an enzyme‐immunoassay method. The mean value of ER in papillary carcinoma tissues (4.0 ± 3.6 fmol/mg protein) was higher than that in normal thyroid tissues (0.8 ± 0.4 ...
Y, Mizukami +5 more
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The role of environmental estrogens and autoimmunity [PDF]
Autoimmunity Reviews, 2012 The prevalence of autoimmune diseases has significantly increased over the recent years. It has been proposed that this epidemiological evidence could be in part attributable to environmental estrogens, compounds that display estrogen-like activity and ...
Cecilia Beatrice Chighizola +1 more
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Estrogen and estrogen receptors of breast cancer
Journal of Surgical Oncology, 1975AbstractHuman breast cancer can be divided into a group that contains specific receptor sites for estrogen and a group without such specific estrogen‐binding sites. The presence of specific estrogen receptors in some tumors indicating hormonal dependency has been shown to be of predictive value for endocrine treatment.
V, Sahadevan +3 more
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International Journal of Gynecology & Obstetrics, 1990
The main types of pharmacologic therapy used to treat the hormone deficiency of menopause are parenteral and oral administrations of estrogen. Parenteral administration results in predictable absorption without major intermediary metabolism, whereas all oral estrogens are subject to intestinal metabolism before entering the systemic circulation ...
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The main types of pharmacologic therapy used to treat the hormone deficiency of menopause are parenteral and oral administrations of estrogen. Parenteral administration results in predictable absorption without major intermediary metabolism, whereas all oral estrogens are subject to intestinal metabolism before entering the systemic circulation ...
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Estrogen or estrogen receptor?
Trends in Endocrinology & Metabolism, 2003View Large Image | Download PowerPoint SlideAs a clinical breast oncologist, I was eager to review Endocrine Therapy in Breast Cancer. Hormonal manipulation has been the predominant form of breast cancer treatment for >50 years. Surgical ablation, high-dose estrogens, LHRH agonists and antiestrogens have all shown clinical benefit.
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