Results 261 to 270 of about 82,387 (308)
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Estrogen Receptors and Anti-Estrogen Therapies
2006The realisation that breast cancer growth is regulated by the hormone estrogen led to the development of tamoxifen as the first target-directed cancer drug. Clearly, there is considerable headway to be made in further elucidating estrogen receptor function, in particular in identifying the mechanisms underlying endocrine resistance.
Lakjaya, Buluwela +3 more
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Estrogen and neuroinflammation
Urology, 2001Women have a higher incidence of inflammatory disorders than men and also appear to perceive painful stimuli differently. It has been suggested that neuroinflammation plays a role in painful bladder disorders of uncertain etiology, such as interstitial cystitis.
D E, Bjorling, Z Y, Wang
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1978
Publisher Summary This chapter discusses the estrogens in pregnancy. A notable characteristic of normal human pregnancy is the extensive production of a variety of biologically active substances. These include (1) the protein hormones human chorionic gonadotropin and human placental lactogen, (2) the enzymes heat-stable alkaline phosphatase and ...
M, Levitz, B K, Young
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Publisher Summary This chapter discusses the estrogens in pregnancy. A notable characteristic of normal human pregnancy is the extensive production of a variety of biologically active substances. These include (1) the protein hormones human chorionic gonadotropin and human placental lactogen, (2) the enzymes heat-stable alkaline phosphatase and ...
M, Levitz, B K, Young
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Gynecologic Investigation, 2010
This paper contains: A review of the features implicated in estrogen action on uterine cells: metabolism, transport, entry, cytosol receptor, and first effects. (2) New results concerning the interaction of several estrogens and antiestrogens with the receptor.
C, Geynet +3 more
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This paper contains: A review of the features implicated in estrogen action on uterine cells: metabolism, transport, entry, cytosol receptor, and first effects. (2) New results concerning the interaction of several estrogens and antiestrogens with the receptor.
C, Geynet +3 more
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JAMA: The Journal of the American Medical Association, 1974
IT WAS discovered in the 1940s that synthetic and natural estrogenic hormones increased fat production in chickens. As a result, pellets of diethylstilbestrol (DES) were implanted in young chickens to improve the quality of their carcasses. This practice was discontinued some years ago.
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IT WAS discovered in the 1940s that synthetic and natural estrogenic hormones increased fat production in chickens. As a result, pellets of diethylstilbestrol (DES) were implanted in young chickens to improve the quality of their carcasses. This practice was discontinued some years ago.
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Trends in Endocrinology & Metabolism, 2002
In recent years, we have become increasingly aware that estrogen is a gonadal hormone that exerts diverse non-reproductive actions on multiple organs and in multiple physiological systems. Amongst these, estrogen has profound effects on plasticity and cell survival of the adult brain.
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In recent years, we have become increasingly aware that estrogen is a gonadal hormone that exerts diverse non-reproductive actions on multiple organs and in multiple physiological systems. Amongst these, estrogen has profound effects on plasticity and cell survival of the adult brain.
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Heterogeneity of Estrogen Binding Sites: Relationship to Estrogen Receptors and Estrogen Responses
1980Publisher Summary This chapter discusses the significance of the various forms of estrogen binding sites. Estrogen receptors are macromolecules that bind estrogen to form receptor hormone complexes. These complexes are generally involved with the stimulation of cellular growth and metabolism.
J H, Clark +5 more
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Estrogen, Anti‐Estrogen, and Gender
Annals of the New York Academy of Sciences, 2002Abstract:In Part 1 of this report, we review data on the effects of estrogen (E), the anti‐E tamoxifen (TMX), and testosterone (T) on methamphetamine (METH)‐induced neurotoxicity in female and male CD‐1 mice. Treatment of gonadectomized females with a physiological regimen of E significantly diminished the amount of striatal dopamine (DA) depletion to ...
Dean E, Dluzen, Janet L, McDermott
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The characterization of estrogens
Analytical Biochemistry, 1963Abstract The use of 2,7-dichlorofluorescein as a nondestructive locating reagent for phenolic steroids on chromatograms is described. A procedure has been developed for the adequate characterization of estrogens from natural sources. Starting with less than 5 μg of steroid, this is chromatographed, esterified (formate or acetate), chromatographed ...
T H, SIMPSON, R S, WRIGHT
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