The rodent uterotrophic assay: Critical protocol features, studies with nonyl phenols, and comparison with a yeast estrogenicity assay [PDF]
, 1997 The major protocol features of the immature rat uterotrophic assay have been evaluated using a range of reference chemicals. The protocol variables considered include the selection of the test species and route of chemical administration, the age of the ...
Ashby, J +7 more
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Ecotoxicology and Environmental SafetyEstrogens have attracted extensive attention because of their harmful effects on organisms such as endocrine disturbance and reproductive toxicity. This study investigated the spatial and temporal distribution and ecological risk assessment of 7 targeted
Jiamei Wang +8 more
doaj +1 more source
Roles of Estrogens in the Healthy and Diseased Oviparous Vertebrate Liver
Metabolites, 2021 The liver is a vital organ that sustains multiple functions beneficial for the whole organism. It is sexually dimorphic, presenting sex-biased gene expression with implications for the phenotypic differences between males and females.
Blandine Tramunt +5 more
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Reference Profile Correlation Reveals Estrogen-like Trancriptional Activity of Curcumin [PDF]
, 2010 Background: Several secondary metabolites from herbal nutrient products act as weak estrogens (phytoestrogens), competing with endogenous estrogen for binding to the estrogen receptors and inhibiting steroid converting enzymes.
Albini, Adriana +9 more
core +1 more source
Novel locally active estrogens accelerate cutaneous wound healing-part 2 [PDF]
, 2017 Estrogen deprivation is associated with delayed healing, while estrogen replacement therapy (ERT) accelerates acute wound healing and protects against development of chronic wounds.
Bartoli, Gabriele +12 more
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Estrogen stimulates dimethylarginine dimethylaminohydrolase activity and the metabolism of asymmetric dimethylarginine. [PDF]
, 2003 Background— Experimental evidence suggests that estrogens stimulate the production of nitric oxide (NO) by vascular endothelial cells. This effect has been attributed to increased expression and enzymatic activity of both the constitutive and inducible ...
Cartwright, JE +3 more
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Metabolomic profiling unravels DNA adducts in human breast that are formed from peroxidase mediated activation of estrogens to quinone methides. [PDF]
PLoS ONE, 2013 Currently there are three major hypotheses that have been proposed for estrogen induced carcinogenicity, however exact etiology remains unknown. Based on the chemical logic, studies were undertaken to investigate if estrogens could generate quinone ...
Nilesh W Gaikwad
doaj +1 more source
A new method for the separation of androgens from estrogens and for the partition of estriol from the estrone-estradiol fraction: with special reference to the identification and quantitative microdetermination of estrogens by ultraviolet absorption spectrophotometry [PDF]
, 1948 It is recognized generally that a qualitative and quantitative knowledge of the excretion pattern of the urinary estrogens is one index to an understanding of the functional activity of the ovary and adrenal cortex.
Friedgood, Harry B. +2 more
core
Endocrine disruptors in bottled mineral water : total estrogenic burden and migration from plastic bottles [PDF]
, 2009 Background, aim, and scope Food consumption is an important route of human exposure to endocrine-disrupting chemicals. So far, this has been demonstrated by exposure modeling or analytical identification of single substances in foodstuff (e.g ...
Oehlmann, Jörg, Wagner, Martin
core +1 more source
The Pros and Cons of Estrogens in Prostate Cancer: An Update with a Focus on Phytoestrogens
BiomedicinesThe role of estrogens in prostate cancer (PCa) is shrouded in mystery, with its actions going from angelic to devilish. The findings by Huggins and Hodges establishing PCa as a hormone-sensitive cancer have provided the basis for using estrogens in ...
Marília I. Figueira +7 more
doaj +1 more source