Results 71 to 80 of about 58,017 (220)
Andrology, EarlyView.ABSTRACT Background Traditionally, Klinefelter syndrome (KS) was considered a clinical condition associated with hyperestrogenism. Aim To compare circulating sex steroids, particularly estrogens, in a cohort of KS and non‐KS hypogonadal men. Materials and Methods A cohort of hypogonadal men, treated and untreated, was prospectively enrolled in a real ...
Daniele Renda Livraghi +8 more
wiley +1 more source
, 2011 Preparation and characterisation of core-shell CNTs@MIPs nanocomposites and selective removal of estrone from water samplesThis paper reports the preparation of carbon nanotubes (CNTs) functionalized with molecularly imprinted polymers (MIPs) for ...
陈朗星 +6 more
core +1 more source
Binding of Estrone to Microfiltration Hollow Fibre Membranes in Filtration of Solutions Containing Trace Estrone [PDF]
, 2002 Increased concern is being paid to the health and environmental risk caused by trace natural and synthetic hormones discharged from sewage treatment plant (STPs).
Schäfer, Andrea +3 more
core +3 more sources
Glucocorticoids modulate drug transporter function in human fetal brain endothelial cells
The Journal of Physiology, EarlyView.Abstract figure legend P‐glycoprotein and breast cancer resistance protein are the most prominent drug transporters at the fetal blood–brain barrier. We isolated primary human fetal brain endothelial cells from early and mid‐gestation cerebral microvessels and exposed them to glucocorticoids cortisol and dexamethasone in vitro.
Nikola Ivanovski +3 more
wiley +1 more source
Estrogen associations with human pregnancy related increases in cytochrome P450 3A activity
Frontiers in PharmacologyIntroductionIncreased CYP3A-mediated drug clearance during pregnancy can lead to subtherapeutic dosing of CYP3A substrates. Pregnancy-related hormones (PRHs) increase CYP3A4 expression and activity in cultured human hepatocytes.
Muluneh M. Fashe +8 more
doaj +1 more source
The first Pd-catalyzed Buchwald–Hartwig aminations at C-2 or C-4 in the estrone series
Beilstein Journal of Organic Chemistry, 2018 A facile Pd-catalyzed C(sp2)–N coupling to provide a range of 2- or 4-[(subst.)phenyl]amino-13α-estrone derivatives has been achieved under microwave irradiation.
Ildikó Bacsa +5 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor +4 more
wiley +1 more source
Estrone-Based Derivatives Stabilize the c‑MYC and c‑KIT G‑Quadruplex DNA Structures
G-rich sequences are present across the genome and can fold to form dynamic secondary structures, namely, G-quadruplexes (G4). These structures play a pivotal role in regulating numerous biological processes including replication, transcription, and ...
Satendra Kumar (535571) +4 more
core +1 more source
工程科学与技术, 2013 :Three co-existing steroid estrogens of estrone (E1),17β-estradiol (E2) and 17α-ethinyl estradiol (EE2) were selected to simulate combined polluted aqueous system and UV(/H2O2/TiO2) was used to control coexisted micropollutants simultaneously.Results ...
马晓雁 +5 more
doaj
(E)-16-(4-Chlorobenzylidene)estrone
Acta Crystallographica Section E, 2013 In the title compound, C25H25ClO2, the C ring adopts a chair conformation, while the B ring approximates a half-chair conformation. The five-membered ring D has a twist conformation on the C—C bond fused with the C ring.
P. L. Nilantha Lakshman +4 more
doaj +1 more source