Results 81 to 90 of about 64,198 (266)
Validation of grizzly bear hair hormone profiles as a tool to monitor population demographics
We measured 16 steroid and thyroid hormone concentrations in grizzly bear hair to predict sex, age class, and reproductive status. Models were highly accurate when predicting sex and age class and showed promise for assessing reproductive status. Results illustrate the potential for hair hormone profiles as non‐invasive population monitoring tools ...
Abbey E. Wilson +10 more
wiley +1 more source
Estrone‐α‐2DG, synthesized via a one‐pot multi‐enzyme system, selectively inhibits aromatase (IC50 = 0.101μM) and triple negative breast cancer cells (IC50 = 20.46 μM), offering a dual function therapeutic scaffold. ABSTRACT Aromatase inhibitors (AIs) are vital in the treatment of estrogen‐dependent breast cancer, especially in postmenopausal women. In
Tzu‐Yu Huang +5 more
wiley +1 more source
The first Pd-catalyzed Buchwald–Hartwig aminations at C-2 or C-4 in the estrone series
A facile Pd-catalyzed C(sp2)–N coupling to provide a range of 2- or 4-[(subst.)phenyl]amino-13α-estrone derivatives has been achieved under microwave irradiation.
Ildikó Bacsa +5 more
doaj +1 more source
ABSTRACT Objective In boys, constitutional delay of growth and puberty (CDGP) has been associated with diverse negative psychosocial effects. Albeit alleviating distress is one of the main reasons for inducing pubertal development, the impact of puberty‐promoting treatment on psychosocial wellbeing is under‐researched.
Laura Kariola +12 more
wiley +1 more source
The important roles of steroid sulfatase and sulfotransferases in gynecological diseases
Gynecological diseases such as endometriosis, adenomyosis and uterine fibroids, and gynecological cancers including endometrial cancer and ovarian cancer, affect a large proportion of women.
Tea eLanisnik Rizner
doaj +1 more source
Antibiotic‐mediated disruption of commensal microbiota increases corneal cholesterol sulfate (CS) production through upregulation of SULT2B1, resulting in impaired corneal epithelial wound healing. Elevated CS suppresses neutrophil recruitment and epithelial cell migration via inhibition of the DOCK2–Rac pathway.
Mamoru Ogawa +6 more
wiley +1 more source
Metabolic clearance rates and interconversions of estrone and 17β-estradiol in normal males and females [PDF]
Christopher Longcope +2 more
openalex +1 more source
Enantioselective Synthesis of (+)-Estrone Exploiting a Hydrogen Bond-Promoted Diels−Alder Reaction
Starting from Dane’s diene and methylcyclopentenedione, (+)-estrone is synthesized along the Quinkert−Dane route in 24% total yield. The key step is an enantioselective Diels−Alder reaction promoted by an amidinium catalyst as efficiently as by a ...
M. Weimar +3 more
semanticscholar +1 more source
Profile of Estrogen Metabolism in Endometriosis Patients
Objective: To assess the estrone (E1), estradiol (E2) and estriol (E3) blood level and its ratio (E2:E1, E2:E3 and E1:E3) between women with and without endometriosis.
Tirsa Verani, Kanadi Sumapradja
doaj +1 more source
16Alpha-hydroxylation of estrone by human cytochrome P4503A4/5 [PDF]
Zhuoshan Huang
openalex +1 more source

