Results 81 to 90 of about 64,198 (266)

Validation of grizzly bear hair hormone profiles as a tool to monitor population demographics

open access: yesThe Journal of Wildlife Management, Volume 90, Issue 2, February 2026.
We measured 16 steroid and thyroid hormone concentrations in grizzly bear hair to predict sex, age class, and reproductive status. Models were highly accurate when predicting sex and age class and showed promise for assessing reproductive status. Results illustrate the potential for hair hormone profiles as non‐invasive population monitoring tools ...
Abbey E. Wilson   +10 more
wiley   +1 more source

Estrone‐α‐2‐Deoxy‐Glucoside as a Targeted Therapy for Triple‐Negative Breast Cancer: Aromatase Inhibition and Cytotoxicity

open access: yesChemical Biology &Drug Design, Volume 107, Issue 2, February 2026.
Estrone‐α‐2DG, synthesized via a one‐pot multi‐enzyme system, selectively inhibits aromatase (IC50 = 0.101μM) and triple negative breast cancer cells (IC50 = 20.46 μM), offering a dual function therapeutic scaffold. ABSTRACT Aromatase inhibitors (AIs) are vital in the treatment of estrogen‐dependent breast cancer, especially in postmenopausal women. In
Tzu‐Yu Huang   +5 more
wiley   +1 more source

The first Pd-catalyzed Buchwald–Hartwig aminations at C-2 or C-4 in the estrone series

open access: yesBeilstein Journal of Organic Chemistry, 2018
A facile Pd-catalyzed C(sp2)–N coupling to provide a range of 2- or 4-[(subst.)phenyl]amino-13α-estrone derivatives has been achieved under microwave irradiation.
Ildikó Bacsa   +5 more
doaj   +1 more source

Puberty‐Promoting Treatment and Psychosocial Well‐Being in Boys With Constitutional Delay of Puberty: A Randomized Controlled Trial

open access: yesClinical Endocrinology, Volume 104, Issue 2, Page 139-146, February 2026.
ABSTRACT Objective In boys, constitutional delay of growth and puberty (CDGP) has been associated with diverse negative psychosocial effects. Albeit alleviating distress is one of the main reasons for inducing pubertal development, the impact of puberty‐promoting treatment on psychosocial wellbeing is under‐researched.
Laura Kariola   +12 more
wiley   +1 more source

The important roles of steroid sulfatase and sulfotransferases in gynecological diseases

open access: yesFrontiers in Pharmacology, 2016
Gynecological diseases such as endometriosis, adenomyosis and uterine fibroids, and gynecological cancers including endometrial cancer and ovarian cancer, affect a large proportion of women.
Tea eLanisnik Rizner
doaj   +1 more source

The Microbiome Modulates Corneal Wound Healing via the Induction of Cholesterol Sulfotransferase Pathway

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Antibiotic‐mediated disruption of commensal microbiota increases corneal cholesterol sulfate (CS) production through upregulation of SULT2B1, resulting in impaired corneal epithelial wound healing. Elevated CS suppresses neutrophil recruitment and epithelial cell migration via inhibition of the DOCK2–Rac pathway.
Mamoru Ogawa   +6 more
wiley   +1 more source

Enantioselective Synthesis of (+)-Estrone Exploiting a Hydrogen Bond-Promoted Diels−Alder Reaction

open access: yesJournal of Organic Chemistry, 2010
Starting from Dane’s diene and methylcyclopentenedione, (+)-estrone is synthesized along the Quinkert−Dane route in 24% total yield. The key step is an enantioselective Diels−Alder reaction promoted by an amidinium catalyst as efficiently as by a ...
M. Weimar   +3 more
semanticscholar   +1 more source

Profile of Estrogen Metabolism in Endometriosis Patients

open access: yesIndonesian Journal of Obstetrics and Gynecology, 2014
Objective: To assess the estrone (E1), estradiol (E2) and estriol (E3) blood level and its ratio (E2:E1, E2:E3 and E1:E3) between women with and without endometriosis.
Tirsa Verani, Kanadi Sumapradja
doaj   +1 more source

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