Results 121 to 130 of about 32,571 (297)

Effect of metformin on inflammation and bone damage in a rat model of medication‐related osteonecrosis of the jaw

open access: yesEuropean Journal of Oral Sciences, Volume 134, Issue 1, February 2026.
Abstract This study investigated how chronic metformin administration modulates the cellular profile and inflammatory markers in a zoledronic acid‐based rat model of medication‐related osteonecrosis of the jaw (MRONJ). Male Wistar rats were allocated to different treatments: (i) naïve, (ii) MRONJ (zoledronic acid, 0.2 mg/kg, i.v.
Liviane Maria Alves Rabelo   +10 more
wiley   +1 more source

Immunomodulatory dynamics in the porcine myometrium: global transcriptome analysis, including the effects of PPARγ ligands

open access: yesBMC Genomics
Background The myometrium is involved in many processes during pregnancy and the estrous/menstrual cycle. Peroxisome proliferator-activated receptors (PPARs) can be regulators of the processes occurring in the myometrium.
Aleksandra Kurzynska   +4 more
doaj   +1 more source

Endometrial Collagen in Woolly Monkey (Lagothrix l. poeppiggi) and the Uakari (Cacajao calvus)

open access: yesJournal of Medical Primatology, Volume 55, Issue 1, February 2026.
ABSTRACT Introduction This study microscopically characterizes collagen changes and their relationship with endometrial architecture in two Neotropical primates. Methods Uterine fragments from six Lagothrix l. poeppigii and six Cacajao calvus in different reproductive phases were histologically processed using Picrosirius Red staining.
Thyago Habner de Souza Pereira   +6 more
wiley   +1 more source

Inhibitory GABAergic Neuron Loss due to Oxidative Damage During Ex Vivo Acute Brain Slice Preparation Influences Genesis and Dynamics of Epileptiform Activity

open access: yesJournal of Neurochemistry, Volume 170, Issue 2, February 2026.
Ex vivo brain slice preparation is a popular technique in neuroscience research with many variations in preparation method. We compared two popular variations in brain slice preparation and found that the choice of brain slice preparation technique significantly affects the viability of neuronal preparation.
Felix Chan   +12 more
wiley   +1 more source

TNF/TNFR1 is a Key Regulator of Prolonged Fasting‐Induced Decrease in Adipose Tissue

open access: yesThe FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Fasting triggers an inflammatory response and increases sympathetic tone in white adipose tissue (WAT), promoting fat breakdown and tissue remodeling. Fasting sparks an inflammatory response that underpins the reduction in adipocyte size and WAT remodeling.
Amanda Carla Clemente de Oliveira   +12 more
wiley   +1 more source

Human Endometrial Extracellular Matrix Hydrogel Facilitated Endometrial Mesenchymal Stem Cells for Endometrial Regeneration

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
Adequate thickness of the uterine lining is crucial for women with thin or damaged endometrium to achieve pregnancies. Endometrial mesenchymal stem cells (eMSC) can facilitate the cyclical repair and regeneration of the human endometrium. In this study, the human endometrium derived extracellular matrix hydrogel supports the growth of eMSC promoting ...
Jingwen Xu   +9 more
wiley   +1 more source

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