Results 141 to 150 of about 57,832 (298)

Sex‐specific metabolic responses to glucagon receptor agonism and modulation of the FGF21‐glucagon axis in female mice

The Journal of Physiology, EarlyView.
Abstract figure legend Therapies targeting the glucagon receptor are being explored for obesity treatment, yet most preclinical studies remain male biased. In this study, Merrild and Johansen et al. show that in diet‐induced obese wild‐type mice a long‐acting glucagon analogue (LA‐Gcg) elicits sexually dimorphic effects on weight loss, food intake ...
Christoffer Merrild, Valdemar Brimnes Ingemann Johansen, Christoffer Clemmensen, Pablo Ranea‐Robles   +3 more
wiley   +1 more source

Ingestion of Amniotic Fluid Enhances\ud Opiate Analgesia in Rats [PDF]

, 1986
Placenta ingestion has recently been shown to enhance opiate-mediated analgesia produced by morphine injection, footshock, or vaginal/cervical stimulation.
Abbott, Patricia, Kristal, Dr. Mark B., Thompson, Alexis C.   +2 more
core  

Distinct Effects of Nonselective Rho‐Kinase Inhibitor Fasudil and Selective Rho‐Kinase 2 Inhibitor KD025 on Serotonin and Dopamine Release in the Nucleus Accumbens of Mice

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
Fasudil perfusion in the NAc increased basal extracellular serotonin but not dopamine, and suppressed depolarization‐evoked release of both. In contrast, KD025 showed minimal effects on basal levels and selectively suppressed evoked serotonin release. ABSTRACT Recent studies have indicated that the Rho GTPase family and Rho‐kinases are associated with ...
Rinako Tanaka, Wenjun Zhu, Taku Nagai, Toshitaka Nabeshima, Kozo Kaibuchi, Norio Ozaki, Hiroaki Ikesue, Hiroyuki Mizoguchi, Kiyofumi Yamada   +8 more
wiley   +1 more source

Age Influences the Bacterial Composition of Samples From Buffaloes in the Marajó Archipelago, Pará, Brazilian Amazon

Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Milk microbiomes showed similar composition in young and adult buffaloes. Despite distinct microbial profiles among matrices, shared bacterial families indicate microbial interaction between milk, faeces, calf spittle and soil. ABSTRACT Buffalo milk stands out for its nutritional qualities and is mainly produced in Brazil in the Amazon region ...
Allana Lais Alves Lima, Savio Souza Costa, Rosiane do Socorro dos Reis, Damazio Campos de Souza, Guilherme Costa Baião, Rennan Garcias Moreira, Herve Louis Ghislain Rogez, Diego Assis das Graças, Rinaldo Batista Viana, Joana Montezano Marques   +9 more
wiley   +1 more source

Endometrial Evaluation Using Video‐Assisted Hysteroscopy After Uterine Prolapse Management in a Mare

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Video‐assisted hysteroscopy for endometrial evaluation following uterine prolapse treatment in a mare. A 6‐year‐old mare presented with complete uterine prolapse after dystocia. Treatment included manual reduction, vulvar suture, antibiotics, anti‐inflammatories and uterine lavage. Five days post‐treatment, video‐assisted hysteroscopy using a dedicated
Gabriela Jaques Rodrigues, Francisco Décio de Oliveira Monteiro, Pedro Paulo Maia Teixeira   +2 more
wiley   +1 more source

Comorbid Alzheimer's Disease and Type 2 Diabetes Microbiota Shape Age‐Associated Gut–Brain Axis Profiles

Aging Cell, Volume 25, Issue 5, May 2026.
Fecal microbiota transplantation from elderly donors with Alzheimer's disease, type 2 diabetes, or both conditions into antibiotic‐treated mice revealed that comorbid microbiota produce the most severe dysbiosis and strongest suppression of hippocampal neurotrophic gene expression.
Alessandro Atzeni, Jonas Mingaila, Gediminas Alzbutas, Rokas Lukoševičius, Justinas Drūteika, Kamila Łuczyńska, Rima Ramonaitė, Tadeusz Pietras, Kasper Sipowicz, Dovilė Kiudelytė, Karolina Keršytė, Emilija Keževičiūtė, Greta Najūtė, Juozas Kupčinskas, Jordi Mayneris‐Perxachs, Daiva Baltriukienė, Aurelijus Burokas   +16 more
wiley   +1 more source

Luteinizing hormone receptor knockout mouse: What has it taught us?

Andrology, Volume 14, Issue 4, Page 1017-1028, May 2026.
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley   +1 more source

Cytochrome P450 1A1 influences obesity‐induced pulmonary hypertension

British Journal of Pharmacology, Volume 183, Issue 9, Page 1824-1844, May 2026.
Background and Purpose The contribution of obesity to pulmonary arterial hypertension (PAH) pathophysiology remains poorly understood. Adipose tissue synthesises estrogens via cytochrome P450 (CYP) 19A1 (aromatase), whereas circulating estrogens are metabolised in the lung by CYP1A1.
Joshua P. Dignam, Smriti Sharma, Gregor Aitchison, Ayman Gebril, Ioannis Stasinopoulos, Sofia Laforest, Chelbi Coyle, Ruth Andrew, Natalie Z. M. Homer, Sébastien Bonnet, Sandra Breuils‐Bonnet, Martin Wabitsch, Margaret R. MacLean   +12 more
wiley   +1 more source

Improving mare fertility via broad ligament imbrication with barbed suture and intracorporeal suturing device

Equine Veterinary Education, Volume 38, Issue 5, Page e243-e248, May 2026.
Summary In this short case series, we report the outcome of four mares undergoing mesometrial imbrication (uteropexy) using barbed suture and an automated laparoscopic suturing device. Medical records of four mares infertile because of delayed uterine clearance (DUC) that underwent laparoscopic mesometrial imbrication to elevate a vertically positioned
A. del Rincon, J. M. O'Leary, A. Derham, C. Hawkes   +3 more
wiley   +1 more source

Investigation of perognathus as an experi- mental organism for research in space biology progress report, 1 apr. - 30 jun. 1965 [PDF]

Reproduction of mice in ...
Gambino, J. J., Lindberg, R. G.
core   +1 more source