Results 161 to 170 of about 57,832 (298)

Cockroach‐Derived Leucokinin VIII Peptide Accelerates Diabetic Skin Wound Healing by Enhancing Keratinocyte Filopodia Formation

Advanced Science, Volume 13, Issue 24, 27 April 2026.
This study identifies the cockroach‐derived peptide leucokinin VIII as a potent accelerator of diabetic wound healing. By activating the FAK‐ACTG1 axis, the peptide drives keratinocyte migration and filopodia formation. Delivered via a developed PLGA‐PEG‐PLGA thermosensitive hydrogel for sustained release, this approach significantly hastens wound ...
Zhengshan Qin, Jinchuan Wu, Xiehua Xiao, Xirui Wang, Nianhui Ding, Xin Zhao, Lu Ma, Jie Li, Lunkun Ma, Cehua Ou, Ning Ma, Jianguo Feng   +11 more
wiley   +1 more source

Intravaginal Progesterone Application as an Efficient and Reproducible Tool for Synchronizing the Mouse Estrous Cycle. [PDF]

Reprod Med Biol
Sato B, Yamashita Y, Shindo M, Sato M, Yamada M, Miyado K, Kawano N.   +6 more
europepmc   +1 more source

Gendering the Menstrual Cycle in Behavioral Neuroendocrinology

American Journal of Human Biology, Volume 38, Issue 4, April 2026.
ABSTRACT The menstrual cycle is increasingly described as a “vital sign of the female body,” with the literature suggesting cycle‐related brain and behavioral changes. With growing interest in the effects that the menstrual cycle has on the brain, body and mind, characterizing what constitutes healthy cycle‐related change has become a central goal of ...
Annie Duchesne, Kiranjot Kaur Jhajj, Nicole White   +2 more
wiley   +1 more source

Estrogen-Mediated Regulation of Fam3d in Mouse Uterus During the Estrous Cycle. [PDF]

Int J Mol Sci
Kim H, Kim B, Kim J, Suh Y, Lee J, Park S, Lee MR, Lee HC, Choi Y.   +8 more
europepmc   +1 more source

Glial cytokine modulation improves sleep and circadian disruption in female SAA knock‐in mice of Alzheimer's‐related pathology

Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract INTRODUCTION Sleep and circadian disturbances are early Alzheimer's disease (AD) features, yet mechanisms linking amyloid pathology, neuroinflammation, and sex differences remain unclear. METHODS We longitudinally assessed sleep, circadian rhythms, and cognition in female and male hAPPSAA knock‐in and control mice from 2 to 19 months using ...
Teresa Macheda, Margaret R. Hawkins, Carrie E. Johnson, Madison G. Lapid, Haleigh R. Whitlock, Savannah M. Shepard, MaKayla F. Cox, Kelly N. Roberts, Leke Bytyqi, Heather M. Hash, Omar A Abou El‐Ezz, Mohammed Abou El‐Ezz, Katherina Kohler, Sridhar Sunderam, Bruce F. O'Hara, Linda J. Van Eldik, Michael P. Murphy, Marilyn J. Duncan, Adam D. Bachstetter   +18 more
wiley   +1 more source

The Role of Dopamine Signaling and Neuroinflammation in Age‐Related Cognitive Dysfunction

Brain and Behavior, Volume 16, Issue 4, April 2026.
We reveal early disruption in synaptic integrity (PSD‐95, synaptophysin, BDNF), increased dopamine clearance (Comt, Net), and inflammatory signaling (Nfkb, Socs3) in the PFC, while the hippocampus remains largely resistant. These molecular “warning signs” precede behavioral deficits, highlighting potential targets for early intervention to protect ...
Junior Bowen, Katie Hanna, Andrew M. J. Young, Gisela Helfer, Samantha L. McLean   +4 more
wiley   +1 more source

Periovulatory neurohormone dynamics reveal an association between secretoneurin and GnRH across the mouse estrous cycle. [PDF]

Front Endocrinol (Lausanne)
Lu C, Peng D, Smith KB, Uju C, Unniappan S, Duarte-Guterman P, Ismail N, Trudeau VL.   +7 more
europepmc   +1 more source

ADAMTS‐7 Increase Contributes to Worsened Neurological Outcome in Mice on High Fat Diet

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
High fat diet (HFD) increases a disintegrin and metalloproteinase‐7 (ADAMTS‐7) in the brain of mice with and without ischemia. Increased ADAMTS‐7 reduces tissue inhibitor of metalloproteinase‐1 (TIMP‐1) to increase matrix metalloproteinase 9 (MMP‐9) activity.
Yang Xu, Jun Li, Zhiyi Zuo
wiley   +1 more source

Screening and analysis of plasma small extracellular vesicle MiRNAs at various estrous cycle phases of goat. [PDF]

J Ovarian Res
Mao S, Mao M, Hou B, Qiu J, Li Y, Sun B, Guo Y, Deng M, Liu D, Liu G.   +9 more
europepmc   +1 more source

Inhaled 5‐HT1B/1D Receptor Antagonist Attenuates Sumatriptan‐Induced Sensitization of Capsaicin‐Sensitive Lung Vagal Afferents: Implications for Preventing Sumatriptan‐Associated Adverse Chest Symptoms

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Our previous study suggests that sumatriptan‐induced chest discomfort is associated with hypersensitivity of CSLV afferents via 5‐HT1B/1D receptors on nerve endings. The present study demonstrates that inhaled 5‐HT1B/1D receptor antagonism suppresses this hypersensitivity without compromising antimigraine efficacy, supporting local pulmonary antagonism
Nai‐Ju Chan, Zung Fan Yuan, Chang‐Chih Kuo, Chun‐Chun Hsu   +3 more
wiley   +1 more source