Results 201 to 210 of about 35,836 (303)

Bifidobacterium animalis BGI‐L99 Ameliorates Polycystic Ovary Syndrome by Modulating the Gut Microbiota‐Bile Acid‐IL‐22 Axis

open access: yesiMetaMed, Volume 2, Issue 2, June 2026.
Polycystic ovary syndrome (PCOS) is described as a complex endocrine‐metabolic disorder frequently accompanied by reproductive dysfunction and depression‐like behaviors. During PCOS progression, gut microbiota dysbiosis and systemic bile acid disturbances co‐occur, severely disrupting host immune and metabolic homeostasis. B.
Haoyu Wang   +18 more
wiley   +1 more source

Bioartificial Livers Developed From Gene‐Edited Pig Hepatocyte Organoids Improve Amino Acid and Lipid Profiles in the Plasma of Patients With Liver Failure

open access: yesMedComm, Volume 7, Issue 6, June 2026.
A bioartificial liver (BAL) integrating GGTA1‐knockout porcine hepatocytes and R‐spondin1‐overexpressing endothelial organoids was tested using plasma from patients with acute‐on‐chronic liver failure (ACLF). The BAL system actively modulates amino acid and lipid metabolism, enhances detoxification, partially restores overall metabolic balance, and ...
Yuting He   +8 more
wiley   +1 more source

Distinct Effects of Nonselective Rho‐Kinase Inhibitor Fasudil and Selective Rho‐Kinase 2 Inhibitor KD025 on Serotonin and Dopamine Release in the Nucleus Accumbens of Mice

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
Fasudil perfusion in the NAc increased basal extracellular serotonin but not dopamine, and suppressed depolarization‐evoked release of both. In contrast, KD025 showed minimal effects on basal levels and selectively suppressed evoked serotonin release. ABSTRACT Recent studies have indicated that the Rho GTPase family and Rho‐kinases are associated with ...
Rinako Tanaka   +8 more
wiley   +1 more source

Elucidation of the effects of caffeine consumption on estrous cycle, hematology, and lipid profile of female Wistar rats. [PDF]

open access: yesSci Rep
Ogunwole E   +6 more
europepmc   +1 more source

Comparative Sleep Architecture Profiles of Antidepressants in Mice: Pharmacological Characterization of Paroxetine, Sertraline, Duloxetine, Mirtazapine and Vortioxetine

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
This study compared five antidepressants (paroxetine, sertraline, duloxetine, mirtazapine, and vortioxetine) in mice using EEG/EMG, revealing distinct effects on REM and NREM sleep. The figure illustrates changes in sleep architecture during the light phase (ZT0–12).
Junya Maruoka   +6 more
wiley   +1 more source

Age Influences the Bacterial Composition of Samples From Buffaloes in the Marajó Archipelago, Pará, Brazilian Amazon

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Milk microbiomes showed similar composition in young and adult buffaloes. Despite distinct microbial profiles among matrices, shared bacterial families indicate microbial interaction between milk, faeces, calf spittle and soil. ABSTRACT Buffalo milk stands out for its nutritional qualities and is mainly produced in Brazil in the Amazon region ...
Allana Lais Alves Lima   +9 more
wiley   +1 more source

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