Results 21 to 30 of about 32,571 (297)

Gene expression patterns in four brain areas associate with quantitative measure of estrous behavior in dairy cows

BMC Genomics, 2011
Background The decline noticed in several fertility traits of dairy cattle over the past few decades is of major concern. Understanding of the genomic factors underlying fertility, which could have potential applications to improve fertility, is very ...
Veerkamp Roel F, de Wit Agnes AC, Mulder Herman A, Beerda Bonne, Woelders Henri, Kommadath Arun, te Pas Marinus FW, Smits Mari A   +7 more
doaj   +1 more source

A multi-tissue transcriptomic landscape of female mice in estrus and diestrus provides clues for precision medicine

Frontiers in Cell and Developmental Biology, 2022
Female reproductive cycle, also known as menstrual cycle or estrous cycle in primate or non-primate mammals, respectively, dominates the reproductive processes in non-pregnant state.
Yiran Zhou, Yiran Zhou, Yiran Zhou, Han Yan, Wenjun Liu, Chengqing Hu, Yuan Zhou, Yuan Zhou, Ruya Sun, Ruya Sun, Yida Tang, Chao Zheng, Jichun Yang, Qinghua Cui, Qinghua Cui   +14 more
doaj   +1 more source

Influence of Estrous Cycle Hormonal Fluctuations and Gonadal Hormones on Neurogenesis in the Subventricular Zone of Adult Mice

مجله دانشگاه علوم پزشکی گرگان, 2022
Background and Objective: Neurogenesis is the process through which neurons are generated from neural stem cells. This process has been shown to occur in special zones of the adult brain including the subventricular zone (SVZ) of the lateral ventricles ...
Mandana Emamdust, Mohammad Taghi Ghorbanian, Fariba Banaian   +2 more
doaj  

Airway exposure to multi-walled carbon nanotubes disrupts the female reproductive cycle without affecting pregnancy outcomes in mice

Particle and Fibre Toxicology, 2017
Background The use of multiwalled carbon nanotubes (MWCNT) is increasing due to a growing use in a variety of products across several industries. Thus, occupational exposure is also of increasing concern, particularly since airway exposure to MWCNTs can ...
H. K. L. Johansson, J. S. Hansen, B. Elfving, S. P. Lund, Z. O. Kyjovska, S. Loft, K. K. Barfod, P. Jackson, U. Vogel, K. S. Hougaard   +9 more
doaj   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

Advanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li, Yanjie Guo, Jianlin Li, Yimeng Li, Leqian Lin, Hoi Kit Matthew Leung, Qingqing Zhang, Kai‐Fai Lee, Ka‐Wang Cheung, Ernest H. Y. Ng, William S. B. Yeung, Philip C. N. Chiu, Cheuk‐Lun Lee   +12 more
wiley   +1 more source

The murine female intestinal microbiota does not shift throughout the estrous cycle.

PLoS ONE, 2018
Pregnancy is accompanied by maternal physiological adaptations including metabolic, endocrine, immune, cardiovascular, skeletomuscular and neurological modifications that facilitate fetal and placental growth and development.
Jessica G Wallace, Ryan H Potts, Jake C Szamosi, Michael G Surette, Deborah M Sloboda   +4 more
doaj   +1 more source

The Pivotal Role of GR‐CAR Pathway in Fetal Programming of Hepatic Cytochrome P450 3A Alteration in Adulthood

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) persistently upregulates hepatic CYP3A1/CYP2B1 in offspring via glucocorticoid receptor (GR) activation. In vivo and in vitro studies show GR promotes P300/CBP binding to the constitutive androstane receptor (CAR) promoter, sustaining histone acetylation (H3K9/K27ac) and enhancing CYP expression. The GR–CAR pathway
Xiaoxiang Sun, Jie Liu, E Xiang, Xia Li, Xuerong Yan, Yuxi Wang, Feng Li, Hao Kou, Hui Wang, Yu Guo   +9 more
wiley   +1 more source

Hippocampal GABAA Receptor and Pain Sensitivity during Estrous Cycle in the Rat [PDF]

Iranian Journal of Medical Sciences, 2011
Background: Estradiol and progesterone as well as hippocampal GABAA receptors are believed to play a role in the modulation of pain. The aim of present study was to investigate the effect of intrahippocampal injections of GABAA receptor agonist (muscimol)
Mahnaz Taherianfard, Mahnaz Mosavi
doaj  

Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits

Advanced Science, EarlyView.
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao, Hanpeng Luo, Dailu Guan, Xuefeng Fu, Feng Wang, Guoming Zhang, Shanglai Li, Hua Yang, Yanli Zhang   +8 more
wiley   +1 more source