Results 61 to 70 of about 66,616 (284)
Animal Models and Experimental Medicine, EarlyView.We identified 45% HFD as the optimal formulation to establish a juvenile rat model of obesity‐related precocious puberty. It elicits robust phenotypic (early vaginal opening, obesity), histological (advanced ovarian development), and endocrine (elevated HPG axis hormones) alterations, with leptin‐mediated GnRH secretion as a core mechanistic driver ...
Jiayi Gong +5 more
wiley +1 more source
ESTRUS SYNCHRONIZATION WITH MEDROXYPROGESTERONE ACETATE IMPREGNATED SPONGES IN GOATS (CAPRA HIRCUS) [PDF]
Pakistan Veterinary Journal, 2009 An experiment was performed to synchronize estrus in goats by locally prepared progesterone-impregnated sponges and to determine the time of onset and duration of estrus alongwith subsequent fertility rate.
R. KAUSAR, S. A. KHANUM, M. HUSSAIN AND M. S. SHAH
doaj
Jurnal Peternakan Indonesia, 2023 Penelitian ini memberikan informasi mengenai kinerja reproduksi kerbau betina di peternakan rakyat Kabupaten Klaten. Penelitian ini telah dilakukan pada April-September 2021 di Kabupaten Klaten.
Faris Tio Kurniawan +6 more
doaj +1 more source
A preclinical mouse model mimicking the ovarian cancer‐induced estrogen deficiency‐depression axis
Animal Models and Experimental Medicine, EarlyView.A preclinical mouse model of ovarian cancer–related depression was developed by combining intraperitoneal tumor cell injection, ovariectomy, and chronic restraint stress. The model replicates key clinical features including estrogen deficiency, depressive‐like behaviors, and tumor progression, and provides a reliable tool for studying the endocrine ...
Jiamin Liu +6 more
wiley +1 more source
Re-evaluation of the first synthetic estrogen, 1-keto-1,2,3,4-tetrahydrophenanthrene, and bisphenol A, using both the ovariectomised rat model used in 1933 and additional assays [PDF]
, 2000 1-Keto-1,2,3,4-tetrahydrophenanthrene (THP-1) was reported by Cook et al in 1933 as the first synthetic estrogen. Estrogenic activity was assessed by the induction of vaginal cornification in ovariectomised rats.
Ashby, J +5 more
core +1 more source
Animal Models and Experimental Medicine, EarlyView.Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma +2 more
wiley +1 more source
Evaluation of Level of Milk Potential on Nutrient Balance in 2- and 4- Year- Old May- Calving Range Cows Grazing Sandhills Upland Range [PDF]
, 2020 A modeling study evaluated the effects of milk production level on nutrient balance in May- calving cows grazing Sandhills upland range during the breeding season. Forage quality of upland range peaks in June and steadily declines in July until November.
Adams, Don C., Mulliniks, J. Travis
core +1 more source
Animal Models and Experimental Medicine, EarlyView.To address the limitations of existing models, this study innovatively established a mouse model of endometriosis (EMs) capable of mimicking cyclic bleeding. Our results confirmed that this model recapitulates the complete pathological progression from ectopic lesion establishment to systemic responses, exhibiting superior clinical relevance compared ...
Yu Zhuang +7 more
wiley +1 more source
The Anatomical Record, EarlyView.Abstract The equine ovary exhibits unique structural and developmental features that distinguish it from those of other domestic species, including the presence of an ovulation fossa and an inversion of cortical and medullary layers. This study aimed to investigate the morphostructural development of the equine fetal ovary, with particular emphasis on ...
Laura Ver Goltz +5 more
wiley +1 more source
Circadian regulation of reproduction: From gamete to offspring [PDF]
, 2013 P01326625; Grants: GNT0519315Few challenges are more critical to the survival of a species than reproduction. To ensure reproductive success, myriad aspects of physiology and behaviour need to be tightly orchestrated within the animal, as well as timed ...
Boden, M., Kennaway, D., Varcoe, T.
core +1 more source