Results 151 to 160 of about 1,697 (183)

Dietary Salt Administration Decreases Enterotoxigenic Bacteroides fragilis (ETBF)-Promoted Tumorigenesis via Inhibition of Colonic Inflammation [PDF]

International Journal of Molecular Sciences, 2020
Consumption of a Western-type diet has been linked to gut-microbiota-mediated colon inflammation that constitutes a risk factor for colorectal cancer. A high salt diet (HSD) exacerbates IL-17A-induced inflammation in inflammatory bowel disease and other autoimmune diseases.
Ki-Jong Rhee, Soonjae Hwang, Minjeong Jo
exaly   +4 more sources

Protective Effects of Zerumbone on Colonic Tumorigenesis in Enterotoxigenic Bacteroides fragilis (ETBF)-Colonized AOM/DSS BALB/c Mice [PDF]

International Journal of Molecular Sciences, 2020
Chronic inflammation has been linked to colitis-associated colorectal cancer in humans. The human symbiont enterotoxigenic Bacteroides fragilis (ETBF), a pro-carcinogenic bacterium, has the potential to initiate and/or promote colorectal cancer. Antibiotic treatment of ETBF has shown promise in decreasing colonic polyp formation in murine models of ...
Ki-Jong Rhee, Soonjae Hwang, Chang Gun Lee   +2 more
exaly   +4 more sources

Modeling ETBF-Mediated Colorectal Tumorigenesis Using AOM/DSS in Wild-Type Mice

International Journal of Molecular Sciences
Enterotoxigenic Bacteroides fragilis (ETBF) promotes colitis-associated cancer through the Bacteroides fragilis toxin (BFT), which induces colonic inflammation that can be exacerbated by external stimuli. We found that BALB/c mice infected with ETBF and treated with azoxymethane and dextran sodium sulfate (DSS) developed numerous distal colon polyps ...
Ki-Jong Rhee, Soonjae Hwang
exaly   +4 more sources

Comparison of Microbiological Profile of Enterotoxigenic Bacteroides fragilis (ETBF) Isolates From Subjects With Colorectal Cancer (CRC) or Intestinal Pre-Cancerous Lesions Versus Healthy Individuals and Evaluation of Environmental Factors Involved in Intestinal Dysbiosis

Anaerobe, 2023
The aim of this study was to analyze enterotoxigenic Bacteroides fragilis (ETBF) isolates from colorectal biopsies of subjects with a histological analysis positive for colorectal cancer (CRC), pre-cancerous lesions (pre-CRC) or with a healthy intestinal tissue and to evaluate the environmental factors that may not only concur to CRC development but ...
Patrizia Spigaglia
exaly   +4 more sources

Zerumbone Restores Gut Microbiota Composition in ETBF Colonized AOM/DSS Mice

Journal of Microbiology and Biotechnology, 2020
Colorectal cancer (CRC) is the leading cause of common malignant neoplasm worldwide. Many studies have analyzed compositions of gut microbiota associated with various diseases such as inflammatory bowel diseases (IBD) and colon cancer. One of the most representative bacteria involved in CRC is enterotoxigenic Bacteroides fragilis (ETBF), a species ...
Ki-Jong Rhee, Yong-Bin Eom, Hye-Won Cho
exaly   +4 more sources

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Enterotoxin-Producing Bacteroides fragilis (ETBF) Strains in Stool Samples Submitted for Testing ofClostridium Difficile and Its Toxins

Anaerobe, 1999
Abstract Fifty faecal samples of patients suspected of having diarrhoea associated with Clostridium difficile were studied. Toxins of C. difficile were tested in vivo directly from the faecal sample using Toxin Detection Kits (Oxoid) to detect toxin A and primers for detection genes of Toxin A and B in a PCR test.
Hanna Pituch, Piotr Obuch-Woszczatyński, Piotr Leszczyński   +2 more
exaly   +3 more sources

Zerumbone Suppresses Enterotoxigenic Bacteroides fragilis Infection-Induced Colonic Inflammation Through Inhibition of NF-κΒ

International Journal of Molecular Sciences, 2019
Enterotoxigenic Bacteroides fragilis (ETBF) is human intestinal commensal bacterium and a potent initiator of colitis through secretion of the metalloprotease Bacteroides fragilis toxin (BFT).
Ki-Jong Rhee, Miyong Yun, Soonjae Hwang
exaly   +2 more sources

Strain-Specific Genetic Signatures of Enterotoxigenic Bacteroides fragilis (ETBF) Reveal Bft-2 as a Candidate Biomarker for Colorectal Cancer

Anaerobe
The role of specific gut microbial strains in colorectal cancer (CRC) remains incompletely understood. Enterotoxigenic Bacteroides fragilis (ETBF), particularly its toxin gene (bft) isotypes, has been linked to CRC, but strain-specific contributions need further elucidation.In this case-control study, stool samples from 60 CRC patients and 60 matched ...
Rasoul Yousefi-Mashouf, Yousef Alikhani, Maryam Hasanzarrini   +2 more
exaly   +3 more sources

[Relationships between the enrichment of ETBF, Fn, Hp in intestinal and colorectal cancer].

Zhonghua zhong liu za zhi [Chinese journal of oncology], 2018
Objective: To explore relationships between the enrichment of ETBF, Fn, Hp in feces, tissues and colorectal cancer. Methods: Feces, lesion tissue and adjacent tissue from 24 patients with colorectal cancer and 31 patients with adenomas were collected, and we collected Feces and tissue of 20 healthy control persons.
J, Zhang, X L, Lu, G, Zhao, H T, Shi, Y, Geng, W T, Zhong, L, Dong   +6 more
openaire   +1 more source

Enterotoxigenic Bacteroides fragilis (ETBF) Enhances Colorectal Cancer Cell Proliferation and Metastasis Through HDAC3/miR-139-3p Pathway

Biochemical Genetics
Enterotoxigenic Bacteroides fragilis (ETBF) is believed to promote the malignant process of colorectal cancer (CRC), but the underlying molecular mechanism still needs to be revealed. CRC cells (SW480 and HCT-116) were treated with ETBF strain. Cell proliferation, invasion and, migration were evaluated by cell counting kit 8 assay, EdU assay, colony ...
Xiaoyong, Wu, Chengrui, Yang, Fangyuan, Sun, Yanzhong, Zhang, Yanliang, Wang, Xuzhao, Li, Fengxian, Zheng   +6 more
exaly   +3 more sources