Results 261 to 270 of about 1,472,047 (314)
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Pharmacology & Therapeutics, 1987
Alcohol is metabolized by two pathways in humans: the ADH pathway which accounts for the bulk of the metabolism, and the MEOS pathway which contributes to the increased rate of ethanol elimination at high blood alcohol levels. The increased rate of elimination which results from chronic alcohol consumption is due to an increase in MEOS activity.
D W, Crabb, W F, Bosron, T K, Li
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Alcohol is metabolized by two pathways in humans: the ADH pathway which accounts for the bulk of the metabolism, and the MEOS pathway which contributes to the increased rate of ethanol elimination at high blood alcohol levels. The increased rate of elimination which results from chronic alcohol consumption is due to an increase in MEOS activity.
D W, Crabb, W F, Bosron, T K, Li
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Environmental Science & Technology, 2008
Environmental, social, economic, and food issues brought on by the rapidly expanding ethanol-from-corn industry in the United States are reviewed and discussed.
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Environmental, social, economic, and food issues brought on by the rapidly expanding ethanol-from-corn industry in the United States are reviewed and discussed.
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Annual Review of Pharmacology, 1969
The rate of disappearance of ethanol from the entire body is usually expressed as mg/kg per hr, which has been designated B sub 60. For humans the average B sub 60 is about 100. It is fairly constant for a given person but varies among individuals, with extremes of about 50 and 200. Essentially the same information may be obtained from the slope of the
R B, Forney, R N, Harger
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The rate of disappearance of ethanol from the entire body is usually expressed as mg/kg per hr, which has been designated B sub 60. For humans the average B sub 60 is about 100. It is fairly constant for a given person but varies among individuals, with extremes of about 50 and 200. Essentially the same information may be obtained from the slope of the
R B, Forney, R N, Harger
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Medical Clinics of North America, 1984
The acute and chronic effects of ethanol on pancreatic structure and function are discussed. Acute necrotizing, acute edematous, acute relapsing, chronic relapsing, and painless pancreatitis have an established association with ethanol abuse. The management of these disorders is outlined.
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The acute and chronic effects of ethanol on pancreatic structure and function are discussed. Acute necrotizing, acute edematous, acute relapsing, chronic relapsing, and painless pancreatitis have an established association with ethanol abuse. The management of these disorders is outlined.
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Neurologic Clinics, 1993
Ethanol abuse is associated with a variety of neurologic disturbances. These disturbances result from direct drug effects, drug withdrawal, nutritional deficiency, organ system failure, and other, unidentified factors. In contrast, abuse of sedative-hypnotic drugs produces a more limited spectrum of neurologic involvement, consisting primarily of ...
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Ethanol abuse is associated with a variety of neurologic disturbances. These disturbances result from direct drug effects, drug withdrawal, nutritional deficiency, organ system failure, and other, unidentified factors. In contrast, abuse of sedative-hypnotic drugs produces a more limited spectrum of neurologic involvement, consisting primarily of ...
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Critical Reviews in Toxicology, 2003
This article provides a detailed assessment of the toxicological and pharmacological literature concerning alcohol-induced biphasic dose-response relationships. The assessment reveals that alcohol-induced hormetic-like dose-response relationships are commonly observed, highly generalizeable according to model and endpoint and quantitative feature of ...
Edward J, Calabrese, Linda A, Baldwin
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This article provides a detailed assessment of the toxicological and pharmacological literature concerning alcohol-induced biphasic dose-response relationships. The assessment reveals that alcohol-induced hormetic-like dose-response relationships are commonly observed, highly generalizeable according to model and endpoint and quantitative feature of ...
Edward J, Calabrese, Linda A, Baldwin
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Journal of the American Dietetic Association, 1980
The first step in ethanol metabolism is carried out by two enzyme systems: Alcohol dehydrogenase and cytochrome P-450. The cytochrome P-450 system also detoxifies a wide variety of foreign compounds. On the basis of recent evidence, metabolic reasons are suggested for four well-known consequences of alcoholism: (a) The development of fatty liver; (b ...
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The first step in ethanol metabolism is carried out by two enzyme systems: Alcohol dehydrogenase and cytochrome P-450. The cytochrome P-450 system also detoxifies a wide variety of foreign compounds. On the basis of recent evidence, metabolic reasons are suggested for four well-known consequences of alcoholism: (a) The development of fatty liver; (b ...
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Ontogeny of ethanol elimination and ethanol-induced hypothermia
Alcohol, 2000Ontogeny of ethanol elimination rates and ethanol-induced hypothermia were examined as possible mechanisms contributing to the marked reduction in ethanol sensitivity early in life (Little et al., 1996; Silveri & Spear, 1998) and the notable gender difference in ethanol sleep-time seen in adult animals (Silveri & Spear, 1998).
M M, Silveri, L P, Spear
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Ethanol tolerance and ethanol-drug interactions in the rat
Toxicology and Applied Pharmacology, 1972Abstract Tolerance to the hypnotic effect of ethanol was induced with adifferent time course in adult male and female Holtzman rats by repeated ip administration of ethanol (2.5 g/kg/day). Female rats exhibited tolerance to ethanol after 10 days of treatment and males at 15 days. The extinction of ethanol tolerance was similar in both sexes. Although
G K, Hatfield, T S, Miya, W F, Bousquet
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Acute Ethanol Poisoning and the Ethanol Withdrawal Syndrome
Medical Toxicology, 1988Ethanol, a highly lipid-soluble compound, appears to exert its effects through interactions with the cell membrane. Cell membrane alterations indirectly affect the functioning of membrane-associated proteins, which function as channels, carriers, enzymes and receptors.
B, Adinoff, G H, Bone, M, Linnoila
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