Results 81 to 90 of about 1,123,887 (321)
A potential tumor suppressor role of PLK2 in glioblastoma
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia+5 more
wiley +1 more source
Identification of inhibitors of the Salmonella FraB deglycase, a drug target
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law+6 more
wiley +1 more source
Inhibitory effect of ethanol on ethanol fermentation.
Anaerobic growth of Saccharomyces carlsbergensis LAM 1068 was inhibited completely at the ethanol concentration of Pmg=95g/l. However, carbon dioxide still produced in a Warburg flask at the ethanol concentration higher than 95g/l. The minimum ethanol concentration for complete inhibition of fermentation was Pmf=195g/l.
Tomoko Asakura+2 more
openaire +3 more sources
Immobilization of Saccharomyces Cerevisae cells on water hyacinth stem pieces and application to repeated batch fermentation for ethanol production [PDF]
Water hyacinth (Eichhorniacrassipe) stem pieces were used as supports for Saccharomyces cerevisiae immobilization. The response surface methodology was implemented to maximize the cell immobilization yield.
Le Nhu Ngoc Ta+2 more
doaj
The C. elegans tetraspanin‐7 (tsp‐7) is a homologue of human CD63, which is a negative regulator of autophagy. The C. elegans strain, tm5761, has a dysfunctional (knockout) tsp‐7 gene. When compared to the wild‐type strain, the tm5761 strain shows increased: life‐ and health‐span; thermotolerance, and stress‐induced locomotion.
Brogan Jones+2 more
wiley +1 more source
Autoctonous yeasts having fermentation ability in producing ethanol from Musa (AAB Simmonds) plantain surplus pulp in the Córdoba department of Colombia Resumen: Se evaluó la capacidad fermentativa de levaduras nativas de la zona costanera del ...
Luis Oviedo Zumaqué+2 more
doaj
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei+6 more
wiley +1 more source
Under the influence of alcohol: The effect of ethanol and methanol on lipid bilayers [PDF]
Extensive microscopic molecular dynamics simulations have been performed to study the effects of short-chain alcohols, methanol and ethanol, on two different fully hydrated lipid bilayer systems in the fluid phase at 323 K. It is found that ethanol has a stronger effect on the structural properties of the membranes.
arxiv
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli+15 more
wiley +1 more source