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Ethanol‐Induced Oxidative Stress in the Liver
Alcoholism: Clinical and Experimental Research, 1996Oxygen stress is well recognized to be a key step in the pathogenesis of ethanol‐associated liver injury. Ethanol administration induces an increase in lipid peroxidation either by enhancing the production of oxygen‐reactive species and/or by decreasing the level of endogenous antioxidants.
I, Kurose +4 more
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Impairment of the asialoglycoprotein receptor by ethanol oxidation
Biochemical Pharmacology, 1996It is well established that ethanol exposure impairs the process of receptor-mediated endocytosis in hepatic cells, although the molecular mechanism(s) and the physiological consequence(s) of this impairment are unclear. Because addressing these mechanistic questions is difficult in vivo, we have developed a recombinant cell line of hepatic origin ...
D L, Clemens +5 more
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Acetate and ethanol oxidation by yeast
Irish Journal of Medical Science, 19641. Baker’s yeast metabolises acetate under aerobic conditions and the pH rises steadily due to the replacement of acetate by bicarbonate and carbonate anions. 2. Oxidation of acetate anions, to which the cell is passively impermeable, shows a characteristic induction effect not observed with acetic acid or ethanol which penetrate readily.
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Enzymatic Mechanisms of Ethanol Oxidation in the Brain
Alcoholism: Clinical and Experimental Research, 2006Background: The exact enzymatic mechanisms of ethanol oxidation in the brain are still unclear. The catalase‐mediated oxidation of ethanol was demonstrated in rat brain using incubation of brain homogenates with catalase inhibitors. The role of the alcohol dehydrogenase (ADH) or cytochrome P450–dependent system in this process is possible, but has not
Sergey M, Zimatkin +4 more
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Ethanol Oxidation by Rat Brain in Vivo
Alcoholism: Clinical and Experimental Research, 1980Can brain metabolize ethanol? We present data demonstrating that brain catalase in conjunction with endogenous H2O2 will oxidize ethanol in vivo. The method is based on an H2O2‐dependent inhibition of brain catalase in vivo by 3‐amino‐1,2.4‐triazole and its prevention by ethanol.
G, Cohen, P M, Sinet, R, Heikkila
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The contribution of the stomach to ethanol oxidation in the rat
Life Sciences, 1987To estimate the amount of ethanol that can be oxidized in the stomach, steady-state conditions were created in a group of fed rats by giving a loading dose of ethanol (2 g/kg body wt I.V.) followed by continuous infusion either intravenously or intragastrically. The rate of ethanol oxidation was calculated from the rate of infusion required to maintain
J, Caballeria, E, Baraona, C S, Lieber
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Evidence for Ethanol Oxidation by Kupffer Cells
Alcoholism: Clinical and Experimental Research, 1999Ethanol oxidation in Kupffer cells was investigated by measuring 14C‐acetate formation from 14C‐ethanol, and the role of aldehyde dehydrogenase 2 (ALDH2) in this process was also examined. Formation of 14C‐acetate from 20 mM of 14C‐ethanol was significantly increased in medium‐containing Kupffer cells (9,003 + 2,066 cpm/5 × 106 cells), compared with ...
Y, Nakamura +7 more
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Parallel pathways of ethanol oxidation: The effect of ethanol concentration
Journal of Electroanalytical Chemistry, 2005Abstract In this work, we investigate the effects of ethanol concentration on the yields of CO2, acetic acid and acetaldehyde as electrooxidation products. FTIR spectra show that the main oxidation product at low ethanol concentrations is acetic acid, CO2 being produced to a minor extent.
G.A. Camara, T. Iwasita
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Catalytic oxidation of ethanol over tantalum oxide
Journal of Catalysis, 1972Abstract The reaction of ethanol and oxygen on tantalum oxide has been investigated at 250–320 °C. In the early stages of the reaction, the catalyst activity is rather low and ethanol undergoes dehydration as well as oxidation. However use of the catalyst for a long period causes a remarkable increase in the rate of acetaldehyde formation.
M. Legendre, D. Cornet
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Oxidation of Ethanol on Sn-Mo Oxide Catalysts
Collection of Czechoslovak Chemical Communications, 1992To determine the acidic and basic properties of the title catalysts, the adsorption of NH3 and SO2 was compared using pulse method. It was found that this characteristics undergoes changes when the Sn-Mo catalyst is treated with aqueous potassium hydroxide solutions of different concentrations.
Magdy A. Wassel +2 more
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