Results 41 to 50 of about 791,104 (305)

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Effect of Different Irrigating Solutions on the Apical Sealing Ability of Resin Based Root Canal Sealer

open access: yesAnnals of Abbasi Shaheed Hospital and Karachi Medical & Dental College, 2023
Objective: To assess the effect of different irrigating solutions (Normal saline, 5.25% NaOCl and 90% Ethanol) on apical sealing ability of resin based root canal sealer filled with single cone obturating technique in extracted teeth.
Syed Saqib Raza Naqvi   +5 more
doaj   +2 more sources

Ethanol fuel improves arthropod capture in pitfall traps and preserves DNA

open access: yesZooKeys, 2012
We tested the value of ethanol fuel as a killing solution in terms of sampling efficiency (species richness and accumulated abundance) and DNA preservation of Ensifera ground-dwelling specimens.
Neucir Szinwelski   +4 more
doaj   +1 more source

Extraction and purification of antioxidative flavonoids from Chionanthus retusa leaf

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
In this work, flavonoids from the leaves of Chionanthus retusa were extracted using alcohol, and the extraction yield was optimized by single-factor and orthogonal experiments.
Zhen Wang   +3 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Experimental Study of Ethanol Solution Vacuum Flash Characteristics Under the Effect of Multi-walled Carbon Nanotube

open access: yesZhileng xuebao, 2019
To study the optimum operating condition of industrial ice making, an experimental system of the vacuum flash of ethanol solution under adsorption was designed based on the theory of flash evaporation.
Zhang Xuelai   +6 more
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

PtRu/C and PtRuBi/C Electrocatalysts Prepared in Two Different Ways by Borohydride Reduction for Ethanol Electro-Oxidation

open access: yesInternational Journal of Electrochemical Science, 2010
PtRu/C (50:50) and PtRuBi/C (50:40:10) electrocatalysts were prepared by borohydride reduction using H2PtCl6.6H2O, RuCl3.xH2O and Bi(NO3)3.5H2O as metals sources and Vulcan XC72 as support.
Michele Brandalise   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy