Results 101 to 110 of about 30,487 (240)

Regulation of Ether À-Go-Go-1 Potassium Channel (EAG1) Gene Expression by Serum and TGF-Alpha in Human Liver Cancer Cells [PDF]

, 2013
Muñoz Acuña, Cleber Camacho, María Eugenia Mendoza‐Garrido   +2 more
openalex   +1 more source

Evaluation of cardiac arrhythmia incidence in patients treated with oral moxifloxacin

International Journal of the Cardiovascular Academy, 2019
Background: The effect of moxifloxacin on QT interval is reversible and dose related, mainly provided by weakly but rapidly activated rectifying potassium channel blockade, IKr or human ether-a-go-go-related gene potassium channels.
Casit Olgun Celik, Aylin Yıldırır, Kaan Okyay, İlyas Atar, Mehmet Bülent Özin, İbrahim Haldun Müderrisoğlu   +5 more
doaj   +1 more source

The 5‐HT₂antagonist ketanserin is an open channel blocker of human cardiacether‐à‐go‐go‐related gene (hERG) potassium channels [PDF]

, 2008
Qiang Tang, Z‐Q Li, W Li, Jun Guo, Hsin‐Yun Sun, Xiaoying Zhang, C‐P Lau, H‐F Tse, Shetuan Zhang, Gang Li   +9 more
openalex   +1 more source

In silico Assessment of Pharmacotherapy for Human Atrial Patho-Electrophysiology Associated With hERG-Linked Short QT Syndrome

Frontiers in Physiology, 2019
Short QT syndrome variant 1 (SQT1) arises due to gain-of-function mutations to the human Ether-à-go-go-Related Gene (hERG), which encodes the α subunit of channels carrying rapid delayed rectifier potassium current, IKr.
Dominic G. Whittaker, Dominic G. Whittaker, Jules C. Hancox, Jules C. Hancox, Henggui Zhang, Henggui Zhang, Henggui Zhang, Henggui Zhang   +7 more
doaj   +1 more source

In vitro chronic effects on hERG channel caused by the marine biotoxin Yessotoxin.

Frontiers in Marine Science, 2014
INTRODUCTION Marine algal blooms caused by the overgrowth of marine phytoplankton have increased in frequency and severity in the last years; supposing a worldwide public health problem.
Sara Fernández Ferreiro
doaj   +1 more source

Genotype-Phenotype Relationships in Long QT Syndrome : Role of Mental Stress, Adrenergic Activity and a Common KCNH2 Polymorphism [PDF]

, 2006
Long QT syndrome is a congenital or acquired arrhythmic disorder which manifests as a prolonged QT-interval on the electrocardiogram and as a tendency to develop ventricular arrhythmias which can lead to sudden death.
Paavonen, Kristian
core  

Upregulation of Functional Kv11.1a Isoform Expression by Modified U1 Small Nuclear RNA

, 2018
The KCNH2 or human ether-a go-go-related gene (hERG) encodes the Kv11.1 potassium channel that conducts the rapidly activating delayed rectifier potassium current in the heart.
Gong, Qiuming, Stump, Matthew R., Zhou, Zhengfeng   +2 more
core  

Caracterização de um domínio do C-terminal de um canal de potássio [PDF]

, 2010
Mestrado em Métodos BiomolecularesDomínios que ligam nucleotideos cíclicos (CNBD) regulam muitas vias de sinalização em células procarióticas e eucarióticas.
Carvalho, Maria João Marques de
core   +1 more source

Rescue of Aberrant Gating by a Genetically Encoded PAS (Per-Arnt-Sim) Domain in Several Long QT Syndrome Mutant Human Ether-á-go-go-related Gene Potassium Channels [PDF]

, 2011
Elena C. Gianulis, Matthew C. Trudeau
openalex   +1 more source

Bag1 Co-chaperone Promotes TRC8 E3 Ligase-dependent Degradation of Misfolded Human Ether a Go-Go-related Gene (hERG) Potassium Channels [PDF]

, 2016
Christine Hantouche, Brittany Williamson, William C. Valinsky, Joshua Solomon, Alvin Shrier, Jason C. Young   +5 more
openalex   +1 more source