Results 181 to 190 of about 22,847 (294)

Hippocampal ether-à-go-go1 potassium channels blockade: Effects in the startle reflex and prepulse inhibition

, 2013
A.C. Issy, José Roberto Falco Fonseca, Luis A. Pardo, Walter Stühmer, Elaine Aparecida Del Bel   +4 more
openalex   +1 more source

The Action of a Novel Fluoroquinolone Antibiotic Agent Antofloxacin Hydrochloride on Human‐Ether‐à‐go‐go‐Related Gene Potassium Channel [PDF]

, 2010
Jia Guo, Shengna Han, J. Liu, Xiangmei Zhang, Zhensheng Hu, Jie Shi, Lirong Zhang, Zhong‐Zhong Zhao, Zhao Zhang   +8 more
openalex   +1 more source

Mass spectrometry of dendrimers

Mass Spectrometry Reviews, Volume 44, Issue 5, Page 682-714, September/October 2025.
Abstract Mass spectrometry (MS) has become an essential technique to characterize dendrimers as it proved efficient at tackling analytical challenges raised by their peculiar onion‐like structure. Owing to their chemical diversity, this review covers benefits of MS methods as a function of dendrimer classes, discussing advantages and limitations of ...
McKenna J. Redding, Scott M. Grayson, Laurence Charles   +2 more
wiley   +1 more source

Photoaffinity labeling coupled to MS to identify peptide biological partners: Secondary reactions, for better or for worse?

Mass Spectrometry Reviews, Volume 44, Issue 5, Page 715-756, September/October 2025.
Abstract Affinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a
Astrid Walrant, Emmanuelle Sachon
wiley   +1 more source

Further Structure-Activity Relationship of G Protein-Gated Inwardly Rectifying Potassium Channels 1/2 Activators: Synthesis and Biological Characterization of In Vitro Tool Compounds. [PDF]

ChemMedChem
Nahid S, Rahman FI, Du Y, Spitznagel BD, Singh SK, Chhonker YS, Murry DJ, Weaver CD, Hopkins CR.   +8 more
europepmc   +1 more source

Trafficking of the human ether-a-go-go-related gene (hERG) potassium channel is regulated by the ubiquitin ligase rififylin (RFFL)

, 2018
Karim Roder, Anatoli Y. Kabakov, Karni S. Moshal, Kevin R. Murphy, An Xie, Samuel C. Dudley, Nilüfer N. Turan, Yichun Lu, Calum A. MacRae, Gideon Koren   +9 more
openalex   +1 more source

Upregulation of Functional Kv11.1 Isoform Expression by Inhibition of Intronic Polyadenylation with Antisense Morpholino Oligonucleotides

, 2012
The KCNH2 gene encodes the Kv11.1 potassium channel that conducts the rapidly activating delayed rectifier current in the heart. KCNH2 pre-mRNA undergoes alternative processing; intron 9 splicing leads to the formation of a functional, full-length Kv11 ...
Gong, Qiuming, Stump, Matthew R., Zhou, Zhengfeng   +2 more
core  

The Quinoline Photoremovable Group (PPG) Platform—A Medicinal Chemist's Approach for Photocage Development and Applications

Medicinal Research Reviews, Volume 45, Issue 5, Page 1423-1451, September 2025.
ABSTRACT Photoremovable protecting groups (PPGs) offer a straightforward solution for the temporary inactivation of biologically active substrates and their subsequent controlled release by light irradiation. Their relatively easy design and mode of application have made them useful tools for studying dynamic biological processes in vitro and in vivo ...
Bence Kontra, Zoltán Mucsi, Janez Ilaš, Petra Dunkel   +3 more
wiley   +1 more source

A Cautionary Tale of Combination Ceftriaxone and Lansoprazole: Should Pediatric Clinicians Heed the Warning? [PDF]

J Pediatr Pharmacol Ther
Israel EN, Nichols KR, Knoderer CA.
europepmc   +1 more source

Quantifying Risk of Delayed QT Prolongation of Ipatasertib in Preclinical and Clinical Studies in Cancer Patients. [PDF]

Clin Transl Sci
Poon V, Sutaria D, Prell R, Halpern W, Wong L, Harris A, Wilkins J, Yoshida K, Sane R.   +8 more
europepmc   +1 more source