Results 191 to 200 of about 30,487 (240)

Alanine Mutagenesis Identifies Specific Amino Acids of Nemertide Alpha-1 Activity and Its Binding to Target Receptors. [PDF]

J Nat Prod
Laborde Q, Peigneur S, Jacobsson E, Göransson U, Tytgat J, Andersson HS.   +5 more
europepmc   +1 more source

A Cautionary Tale of Combination Ceftriaxone and Lansoprazole: Should Pediatric Clinicians Heed the Warning? [PDF]

J Pediatr Pharmacol Ther
Israel EN, Nichols KR, Knoderer CA.
europepmc   +1 more source

Biocompatible β-cyclodextrin-based metal-organic frameworks. [PDF]

Front Chem
Wilson K, Cordes DB, McKay AP, Naden AB, Magdysyuk OV, Rainer DN, Armstrong AR, Morris RE, Desai AV, Ettlinger R.   +9 more
europepmc   +1 more source

Polysulfone/Graphene Oxide Mixed Matrix Membranes for Improved CO₂/CH₄ Separation. [PDF]

Membranes (Basel)
Alsaady M, Waqas S, Almarshoud MA, Maqsood K, Abdulrahman A, Yan Y.   +5 more
europepmc   +1 more source

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Propranolol inhibits the human ether-a-go-go-related gene potassium channels

European Journal of Pharmacology, 2005
Propranolol is a noncardioselective beta-adrenergic antagonist that has been recently reported to prolong the QTc interval on the surface electrocardiogram in humans when overdosed [Farhangi, V., Sansone, R.A. (2003). QTc prolongation due to propranolol overdose. Int. J. Psychiatry Med. 33, 201-202.].
Xiaozhou, Yao, Maggie S, McIntyre, Daniel G, Lang, Ivy H, Song, James D, Becherer, Mir A, Hashim   +5 more
openaire   +2 more sources

Direct Block of Human Ether-a-go-go-Related Gene Potassium Channels by Caffeine

The Journal of Pharmacology and Experimental Therapeutics, 2006
The human ether-a-go-go-related gene (hERG) potassium channel is expressed in a variety of cell types, including neurons, tumor cells, and cardiac myocytes. In the heart, it is important for repolarization of the cardiac action potential. Attenuation of hERG current can cause long QT syndrome and cardiac arrhythmias such as torsades de pointes ...
Cockerill, SL, Mitcheson, JS
openaire   +3 more sources

Mallotoxin Is a Novel Human Ether-a-go-go-Related Gene (hERG) Potassium Channel Activator

The Journal of Pharmacology and Experimental Therapeutics, 2006
Human ether-a-go-go-related gene (hERG) encodes a rapidly activating delayed rectifier potassium channel that plays important roles in cardiac action potential repolarization. Although many drugs and compounds block hERG channels, activators of the channel have only recently been described.
Haoyu, Zeng, Irina M, Lozinskaya, Zuojun, Lin, Robert N, Willette, David P, Brooks, Xiaoping, Xu   +5 more
openaire   +2 more sources

Inhibition of HumanEther-A-Go-GoPotassium Channels by Cocaine

Molecular Pharmacology, 2001
Cocaine is a potent cardiac stimulant and its use has been linked to life-threatening arrhythmias in humans. A prominent effect of cocaine in the heart is a suppression of the delayed-rectifier potassium current (I(K)) that is important for cardiac repolarization.
openaire   +2 more sources