Results 41 to 50 of about 298,529 (290)
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Are Greeks’ Unconcerned about Ethical Market Choices?"
An Ethical Unconcern (EthU) scale was constructed and its impact on Positive Ethical Consumption was examined. The procedure of EthU included literature search, brainstorming and discussion groups to generate the preliminary pool of 99 items, refinement ...
Antonia DELISTAVROU, Irene TILIKIDOU
doaj
Ethical qualities in consumption [PDF]
This article seeks to develop an empirically grounded theorization of care. Current care theory tends to be conceived along philosophical, psychological and labour dimensions, with much of the literature focusing on caring labour and, therefore, invoking a productionist orientation.
Shaw, Deirdre +3 more
openaire +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
The role of guilt and pride in consumers’ self-regulation: an exploration on sustainability and ethical consumption [PDF]
Researchers are interested in understanding the individual processes that favour consumers’ self-regulation since they can contribute to the achievement of personal and collective long-term goals in many areas.
Antonetti, Paolo
core
How Do Personal Values Affect Boycott Participation? The Moderating Role of National Culture
The aim of this article is to examine the relationship between personal values and participation in consumer boycotts across countries, taking into account the role of national culture.
Grzegorz Zasuwa, Alicja Węgierak
doaj +1 more source
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Les gens bien mangent bien : comprendre le répertoire culturel de l’alimentation éthique
Ethical consumption is understood by scholars as a key way that individuals can address social and ecological problems. While a hopeful trend, it raises the question of whether ethical consumption is primarily an elite social practice, especially since ...
Josée JOHNSTON +2 more
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source

