Results 41 to 50 of about 1,045,034 (278)

Deciphering Anti‐Cancer Drug Efficacy Through Nanomechanical Vibrations in Living Gastric Cancer Organoids

Advanced Science, EarlyView.
This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang, Qiubo Chen, Shihai Lan, Liang Zhu, Shuaiyu Liu, Yan Xia, Yalu Zhang, Hanhui Yao, Yongman Liu, Shangquan Wu, Qingchuan Zhang   +10 more
wiley   +1 more source

Ethical Dilemmas and Governance Strategies for Research and Clinical Application of Proton Tumor Therapy

Yixue yu zhexue
Throughout the process from research and development to clinical translation, proton therapy for tumors continues to face unresolved issues regarding the management of safety risks and the attribution of responsibility.
Wen CAO, Wenbing MA, Shiyun ZHANG
doaj   +1 more source

GenEth: a general ethical dilemma analyzer

Paladyn, 2018
We argue that ethically significant behavior of autonomous systems should be guided by explicit ethical principles determined through a consensus of ethicists. Such a consensus is likely to emerge in many areas in which intelligent autonomous systems are
Anderson Michael, Anderson Susan Leigh
doaj   +1 more source

Artificial intelligence and healthcare: An ethical dilemma

Bangabandhu Sheikh Mujib Medical University Journal, 2023
not available Bangabandhu Sheikh Mujib Medical University Journal 2023;16(2): 73 ...
Zubair Ahmed Ratan , Md Atiqul Haque
doaj   +1 more source

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

Advanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song, Can Zhao, Qiaoling Wang, Hongjiao Zhang, Xiao Liu, Linqi Wang, Michael Bromley, Wen‐Bing Yin   +7 more
wiley   +1 more source

Digital Dilemma 2018

Papers from the Institute of Archaeology, 2020
To download this paper, please click here.In October 2018 a one-day conference was held at the UCL Institute of Archaeology focussing on the ‘Digital Dilemma’ in biological archaeology —specifically human remains research where the use of digitisation ...
doaj   +2 more sources

Students’ engagement in education as sustainability: Implementing an Ethical Dilemma-STEAM Teaching Model in chemistry learning [PDF]

, 2022
This paper reports the results of a study on the implementation of the Ethical Dilemma STEAM Teaching Model in secondary schools in Jakarta, Indonesia.
Taylor, Elisabeth, Ridwan, A., Mardiah, A., Alin Mardiah, Elisabeth Taylor, Taylor, P.C., Mardiah, Alin, Rahmawati, Y., Taylor, Peter Charles, Ridwan, Achmad, Rahmawati, Yuli, Peter Charles Taylor, Achmad Ridwan, Taylor, E., Yuli Rahmawati   +14 more
core   +1 more source

A 3D‐Printed SFE‐Graded Alloy Mitigates Cryogenic Discontinuous Plastic Flow and Hydrogen Embrittlement

Advanced Science, EarlyView.
A novel strategy features gradient composition and stacking fault energy‐tuned (CoCrMn)100‐2xFexNix fabricated via in situ alloying additive manufacturing. This design circumvents cryogenic discontinuous plastic flow and hydrogen embrittlement of metallic materials under quasi‐static loading and hydrogen‐rich environment relevant to lunar polar ...
Renhao Wu, Ao Geng, Peihao Geng, Hyojin Park, Eun Seong Kim, Sang‐Ho Oh, Stephan Schönecker, Xiaoqing Li, Tianlong Zhang, Shuhui Li, Byeong‐Joo Lee, Hyoung Seop Kim   +11 more
wiley   +1 more source

Ethical dilemma scenarios and emerging technologies

, 2022
S.325-336This paper posits that ethical dilemma scenarios are a useful instrument to provoke policymakers and other stakeholders, to including industry, in considering the privacy, ethical, social and other implications of new and emerging technologies ...
Wright, David, Friedewald, Michael, Venier, Silvia, Finn, Rachel L., Mordini, Emilio, Gutwirth, Serge, Schütz, Philip, Gellert, Raphael   +7 more
core   +2 more sources

High‐Performance Bio‐Based Epoxy Vitrimers and Composites: Synergizing Robustness and Reprocessability via Fractional Free Volume Regulation

Advanced Science, EarlyView.
In this work, two bio‐based epoxy monomers were designed to tune the dynamic network of a rigid–flexible hybrid epoxy through free‐volume control, achieving a synergy among high free volume, high cross‐linking density, and segmental mobility while balancing strength and toughness.
Kai Dong, Di Zhao, Chengji Zhao
wiley   +1 more source