Results 51 to 60 of about 1,045,034 (278)

Gut Microbial Topology and Metabolic Signatures Associated With Colorectal Neoplasia

open access: yesAdvanced Science, EarlyView.
The gut microbiota organizes into two robust association patterns linked to colorectal neoplasia risk. Topological shifts in microbial networks are associated with metabolite alterations and may shape host responses during disease development. ABSTRACT Alterations of gut microbial communities impact health.
Kai Song   +13 more
wiley   +1 more source

Managing Ethical Dilemmas

open access: yes, 2015
This chapter reviews almost a decade of research and writing undertaken by the authors into ethical dilemmas faced by leaders in a number of different operational contexts, including schools, universities and the public sector. The importance of this body of work is emphasised by one of our research participants who argued that ethical dilemmas were ...
Cranston, Neil   +2 more
openaire   +5 more sources

In Situ Photo‑Crosslinked Functional Bilayer Hydrogel Modulates Local Microenvironment and Remyelination After Optic Nerve Injury

open access: yesAdvanced Science, EarlyView.
A blue‐light‐crosslinked bilayer hydrogel was developed for local optic nerve repair. The adhesive GM‐Odex outer layer seals and anchors the lesion, while the non‐adhesive GM‐imid inner layer releases MPDA‐Cle without obstructing CSF flow. This system modulates oxidative and inflammatory microenvironments, supports oligodendrocyte differentiation and ...
Tonghe Pan   +13 more
wiley   +1 more source

Some ethical dilemmas

open access: yesPakistan Journal of Medical Sciences, 2013
.
openaire   +2 more sources

Whistleblowing: an ethical dilemma

open access: yesAustralasian Journal of Information Systems, 1993
Because most organizations depend on computer systems that electronically store important data to perform crucial business functions, the integrity of these information systems is paramount. Securing company systems, however, is not always an easy task.
Joan K. Pierson   +2 more
openaire   +3 more sources

GenEth: A General Ethical Dilemma Analyzer

open access: yes, 2014
We contend that ethically significant behavior of autonomous systems should be guided by explicit ethical principles determined through a consensus of ethicists.
Anderson, Michael   +3 more
core   +1 more source

Scaffold RNA Reengineering for a Leakage‐Suppressed CRISPR/Cas12a Cascade System Toward Precise Nucleic Acid Diagnostics

open access: yesAdvanced Science, EarlyView.
Schematic illustration of the CALCas system, in which a conformational switch in the 3' terminal DNA extension of scaffold RNA (3'D‐SR) drives cascade‐activatable Cas12a cleavage while suppressing leakage. ABSTRACT Amplification‐free CRISPR detection has attracted significant attention for its capacity to circumvent the intricacies of nucleic acid ...
Xingrong Li   +11 more
wiley   +1 more source

A Biomimetic PLK1 Nanodelivery System Promotes Migrasome‐Mediated Mitocytosis to Restore Efferocytosis and Functional Recovery After Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
MM‐NPs@PLK1 are formed by encapsulating PLK1 plasmids within CBP5 and coating the nanocomplexes with macrophage membranes. After macrophage‐associated uptake, the NPs@PLK1 enter the cytoplasm and release the PLK1‐encoding plasmid in response to elevated intracellular ROS levels.
Zhenxin Hu   +13 more
wiley   +1 more source

Ethical Reasoning: The Impact Of Ethical Dilemma, Egoism And Belief In Just World [PDF]

open access: yes, 2005
Following a 3 [dilemma: coercion and control (CC); conflict of interest (CI); personal integrity (PI)] × 2 (egoism: self; organization) × 2 (belief in just world (BJW): strong; weak) between-subjects factorial design, we hypothesized the main effects ...
A. Ansari, Mahfooz   +2 more
core   +4 more sources

The conflict between oral health and patient autonomy in dentistry: a scoping review

open access: yesBMC Medical Ethics
Background Respect for patient autonomy, the principle that patients are capable to make informed decisions about medical interventions, is fundamental in present-day medicine.
Szilárd Dávid Kovács   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy