Results 51 to 60 of about 973,483 (281)

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

open access: yesAdvanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang   +5 more
wiley   +1 more source

To Overcome Ethical Dilemmas in an Organization: Paradox and Ethics of Freedom Can Help [PDF]

open access: yesBusiness Ethics and Leadership
A theoretical model for managers responding to a morally challenging situation is developed in the article. This model explores and examines how managers deal with paradoxes created by ethical dilemmas.
Benoît Cherré, Nathalie Lemieux
doaj   +1 more source

Artificial intelligence and healthcare: An ethical dilemma

open access: yesBangabandhu Sheikh Mujib Medical University Journal, 2023
not available Bangabandhu Sheikh Mujib Medical University Journal 2023;16(2): 73 ...
Zubair Ahmed Ratan , Md Atiqul Haque
doaj   +1 more source

A 3D‐Printed SFE‐Graded Alloy Mitigates Cryogenic Discontinuous Plastic Flow and Hydrogen Embrittlement

open access: yesAdvanced Science, EarlyView.
A novel strategy features gradient composition and stacking fault energy‐tuned (CoCrMn)100‐2xFexNix fabricated via in situ alloying additive manufacturing. This design circumvents cryogenic discontinuous plastic flow and hydrogen embrittlement of metallic materials under quasi‐static loading and hydrogen‐rich environment relevant to lunar polar ...
Renhao Wu   +11 more
wiley   +1 more source

Cross‐scale Material‐Structure Synergy for 2D Metamaterials: Toward Customizable Intelligent Electromagnetic Manipulation in Multiphysics Fields

open access: yesAdvanced Science, EarlyView.
Recent advances in metasurface‐enabled low‐observable technologies are reviewed from the perspective of cross‐scale material–structure synergy. Electromagnetic, thermal, optical, and acoustic stealth are highlighted together with dynamic tuning, programmable coding, data‐driven inverse design, artificial intelligence, multispectral compatibility, and ...
Shuhao Wang   +5 more
wiley   +1 more source

Some ethical dilemmas

open access: yesPakistan Journal of Medical Sciences, 2013
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openaire   +2 more sources

Whistleblowing: an ethical dilemma

open access: yesAustralasian Journal of Information Systems, 1993
Because most organizations depend on computer systems that electronically store important data to perform crucial business functions, the integrity of these information systems is paramount. Securing company systems, however, is not always an easy task.
Joan K. Pierson   +2 more
openaire   +3 more sources

Ethical Issues and Ethical Problems in Psychiatry

open access: yes
Psychiatry is a medical specialty that aims to understand, classify, prevent, treat disorders, and improve mental health. Medical ethics is a discipline that evaluates, analyzes, and discusses ethical principles in the field of medicine, examines the ...
Ekmekci, Perihan Elif, Gürcan, G.
core   +1 more source

Ethical approval in developing countries is not optional [PDF]

open access: yes, 2012
When conducting health and medical research it is not only important to do the research ethically, but also to apply for prior ethical approval from the relevant authorities.
Simkhada, Padam   +3 more
core   +1 more source

High‐Performance Bio‐Based Epoxy Vitrimers and Composites: Synergizing Robustness and Reprocessability via Fractional Free Volume Regulation

open access: yesAdvanced Science, EarlyView.
In this work, two bio‐based epoxy monomers were designed to tune the dynamic network of a rigid–flexible hybrid epoxy through free‐volume control, achieving a synergy among high free volume, high cross‐linking density, and segmental mobility while balancing strength and toughness.
Kai Dong, Di Zhao, Chengji Zhao
wiley   +1 more source

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