Results 131 to 140 of about 109,033 (305)

Developing an inter-university partnership: The importance of relationally-connected leaders

, 2014
We have been involved in an inter-university partnership that supports, contributes to, and influences our own and others’ thinking and actions. As we have collaborated on teaching, learning, and research in the field of educational leadership, we ...
Ferrier-Kerr, Jenny, Ferrier-Kerr, Jenny L., Haxton, Paul   +2 more
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

The Nexus Between Ethical Leadership and Employees’ Perception of Workplace Safety During COVID-19 Under Mediation and Moderation Model

, 2023
Jianmin Sun,1 Muddassar Sarfraz,2 Muhammad Asghar3 1School of Management, Nanjing University of Posts and Telecommunications, Nanjing, People’s Republic of China; 2School of Management, Zhejiang Shuren University, Hangzhou, 310015, People’s Republic of ...
Asghar M, Sarfraz M, Sun J
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Designing and Validating the Ethical Leadership Model in Organizations [PDF]

فرایند مدیریت و توسعه, 2019
Today, in analyzing public organizations, it is necessary for leaders to address ethics and ethical values and be unconditionally committed to the accepted ethical principles so that they may convince their staff to achieve any common goals.
Roghaiieh Fathi-Livari, Ali Hamidizadeh, Nasser Sanoubar, Hassan Zareei-Matin   +3 more
doaj  

Ethical leadership: through the eyes of employees [PDF]

, 2010
Ethical leaders in organizations are important for putting formal ethics programs into practice as they are role models of appropriate behaviors. The four empirical studies included in this dissertation examined the antecedents and outcomes of ethical ...
Kalshoven, K.
core  

Ethical leadership, employee well-being, and helping: the moderating role of human resource management

, 2012
In this multi-source study, we examined the link between ethical leadership, human resource management (HRM), employee well-being, and helping. Based on the Conservation of Resources Theory, we proposed a mediated moderation model linking ethical ...
Kalshoven, K., Boon, C.T.; id_orcid, Boon, C.T.   +2 more
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

School heads’ ethical leadership styles: a case study of selected Gweru district schools in Zimbabwe

Journal of Educational Studies
The subjectivity of ethics in leadership makes ethical decision-making a challenge for school heads, particularly when faced with ethical dilemmas. Informed by Ethical Leadership theory.
Shepherd Shoko
doaj