Results 91 to 100 of about 1,314,449 (310)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Efficacy of Philosophy Training for Children on the Social Responsibility and Ethical Intelligence of 9-12-Year-Old Children [PDF]

open access: yesپژوهش‌های کاربردی روانشناختی
The present study was conducted to investigate the efficacy of philosophy training for children in fostering social responsibility and ethical intelligence in 9-12-year-old children.
Zeinab Ghdiri Bidhendi   +1 more
doaj   +1 more source

Cut-and-Paste Plagiarism: Teaching Student Researchers Boundaries

open access: yes, 2006
Librarians affiliated with educational institutions, as members of an academic community, participate in teaching students and future scholars how they share in the responsibility of upholding ethical standards of scholarship and values of academic ...
Echavarria Robinson, Tami
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

The Pathology of Care

open access: yesŒconomia, 2018
This research explores two conflicting ethical systems. Neoliberalism’s foundations support an overarching ethic of individual autonomy and individual responsibility.
Mary V. Wrenn, William Waller
doaj   +1 more source

Corporate social responsibility and banks [PDF]

open access: yes, 2009
Article discussing ethical issues and matters of social responsibility surrounding turmoil in the capital markets, bank failures and government intervention. Article by Charles Chatterjee (Global Policy Institute, London Metropolitan University) and Anna
Chatterjee, Charles, Lefcovitch, Anna
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Analisis Pengaruh Sifat Machiavellianisme¸ Etika dan Tanggung Jawab Sosial, Faktor Situasional dan Locus Of Control terhadap Pengambilan Keputusan Etis oleh Konsultan Pajak [PDF]

open access: yes, 2018
The following research aimed to study the effect of Machiavellian personality, Perceived Role of Ethics, and Social Responsibility (PRESOR), situational factor, and both internal and external  Locus of control on ethical decision making made by tax ...
Mulyani, S. D. (Susi)   +1 more
core  

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Corporate social responsibility: The involvement of small medium enterprises [PDF]

open access: yes, 2015
The purpose of the paper is to study the involvement of corporate social responsibility by small medium enterprises (SMEs) in Malaysia. Based on the sample taken from SMEs listed under Enterprise 50 (E50) over five years, questionnaires were distributed ...
Ahmad Shukri, Nor Fadhilah   +2 more
core  

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