Results 91 to 100 of about 2,906,189 (349)

Realizing responsibility. Institutional routines, critical intervention, and the “big” questions in the controversy over non-invasive prenatal testing in Germany

open access: yesNew Genetics and Society, 2018
NIPT has become a matter of controversy in Germany over the past years, there is now a widespread concern that it raises fundamental social and ethical questions.
Kathrin Braun, Sabine Könninger
doaj   +1 more source

Designing Virtuous Sex Robots [PDF]

open access: yes, 2019
We propose that virtue ethics can be used to address ethical issues central to discussions about sex robots. In particular, we argue virtue ethics is well equipped to focus on the implications of sex robots for human moral character.
Haselager, Pim, Peeters, Anco
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

MORAL TELEOLOGY IN ETHICAL CRITIQUE OF THE ECONOMISM

open access: yesВісник Київського національного університету імені Тараса Шевченка. Серія Економіка, 2014
The paper considers the moral teleology in terms of ethical critique of the economism. Responsibility as an ethical category is interpreted in terms of economic ethics and taking into account the genetic relationship between the economy and morality. The
H. Ilina
doaj   +1 more source

Credit Markets with Ethical Banks and Motivated Borrowers [PDF]

open access: yes
This paper investigates banks’ corporate social responsibility. Two different competitive credit markets do exist: one for standard projects and one for ethical ones.
Barigozzi, Francesca, Tedeschi, Piero
core  

Ethical Marketing: A Look on the Bright Side [PDF]

open access: yes, 2006
This article offers an alternative to conventional approaches to ethical analysis in business and marketing. We submit that studying companies with exemplary records of ethical conduct and social responsibility offers useful and compelling guidance to ...
Klein, Thomas A.   +2 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Reducing misdiagnosis in AI-driven medical diagnostics: a multidimensional framework for technical, ethical, and policy solutions

open access: yesFrontiers in Medicine
PurposeThis study aims to systematically identify and address key barriers to misdiagnosis in AI-driven medical diagnostics. The main research question is how technical limitations, ethical concerns, and unclear accountability hinder safe and equitable ...
Yue Li   +7 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Ethics-Rorty-cultural studies : towards an understanding of the cultural production of solidarity : a thesis presented in partial fulfillment of the requirements for the degree of Master of Arts in English at Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 2000
Is cultural studies on the verge of an ethical turn? What role could the work of Richard Rorty play in such an ethical turn? Rorty may be considered as a cultural theorist whose work enables a productive articulation of cultural studies and that area of ...
Hunt, Alistair Peter
core  

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