Results 41 to 50 of about 1,311,767 (216)

The features and qualities of online training modules in research ethics: a case study evaluating their institutional application for the University of Botswana

Global Bioethics, 2020
Research ethics remains a cornerstone of the scientific enterprise as it defines the boundaries of responsible conduct of research. Our aim was to systematically identify, review and test online training courses in research ethics which could be ...
Dolly Mogomotsi Ntseane, Joseph Ali, Kristina Hallez, Boikanyo Mokgweetsi, Mary Kasule, Nancy E. Kass   +5 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

International Perspectives and Chinese Practice in the Ethical Review of Brain-Computer Interfaces

Yixue yu zhexue
The rapid development of brain-computer interface (BCI) has posed unprecedented challenges to traditional ethical frameworks, raising core issues related to personal autonomy, privacy protection, risk governance, and social equity. This paper reviews the
Xiaoshan LIANG, Caizhen BAI, Yi YANG, Xiaolin YUE   +3 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Ethical Dilemmas of Brain-Computer Interface Technologies and Products from the Perspective of Ethical Review

Yixue yu zhexue
Brain-computer interface (BCI) technologies and products are not only a medical treatment modality, but also involve the information and privacy protection of individual patients and patient groups, while bearing implications for national biosafety.
Jiuhui LI, Jianyu CHEN, Ruona AN, Xiaoyun CHEN   +3 more
doaj   +1 more source

Conducting Record Review Studies in Clinical Practice [PDF]

Journal of Clinical and Diagnostic Research, 2014
Clinical record review or chart review is a previously recorded data to answer clinical queries. Such a study can be used to answer specific clinical questions in a relatively easy and less resource intensive manner. But these studies may be constrained
Siddharth Sarkar, Divya Seshadri
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Study on exiting problems and countermeasures during implemention of scientific research ethics of nursing staff

Huli yanjiu, 2019
Objective:To analyze the current implementation status and existing problems of nursing staff′s research ethics,and put forward corresponding countermeasures,so as to provide a realistic basis for strengthening the construction of review mechanism on ...
程金莲, 韩世范, 褚银平, 李玉娇, 谭茜, 陈琼   +5 more
doaj  

Exploration of Implementation Paths of Ethical Review in Medical Artificial Intelligence Research: from Perspectives of Algorithmic Transparency and Data Security

Zhongguo yiliao qixie zazhi
Objective From the perspectives of algorithmic transparency and data security to establish a practical and feasible ethical review mechanism for medical artificial intelligence (AI) research, effectively safeguarding the life, health, personal dignity ...
Lanlan HU, Dan LIU, Yue ZHANG, Yuanyuan LI, Yu HU, Meng ZHANG, Yang MAO, Qian DAI, Jianyun ZHOU   +8 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source