Results 51 to 60 of about 12,286,533 (342)
Research on the Ethical Dilemma and Legal Regulation of Clinical Application of 3D Bioprinting
As a cutting-edge interdisciplinary field integrating biomedicine and engineering, 3D bioprinting technology demonstrates revolutionary potential in organ regeneration and precision medicine. Drawing on laws and regulations such as the Biosecurity Law of
Yiping MU +3 more
doaj +1 more source
Refining Housing, Husbandry and Care for Animals Used in Studies Involving Biotelemetry
Biotelemetry can contribute towards reducing animal numbers and suffering in disciplines including physiology, pharmacology and behavioural research.
Penny Hawkins
doaj +1 more source
Ethics review in compassionate use [PDF]
Compassionate use is the use of unapproved drugs outside of clinical trials. So far, compassionate use regulations have been introduced in the US, Canada, many European countries, Australia and Brazil, and treatment on a compassionate use basis may be performed in Japan and China. However, there are important differences between relevant regulations in
Jan Jakub Borysowski +2 more
openaire +3 more sources
Ethical Dilemmas and Privacy Issues in Emerging Technologies: A Review
Industry 5.0 is projected to be an exemplary improvement in digital transformation allowing for mass customization and production efficiencies using emerging technologies such as universal machines, autonomous and self-driving robots, self-healing ...
L. L. Dhirani +3 more
semanticscholar +1 more source
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm +11 more
wiley +1 more source
Exploration of Ethical Review Disputes and Regulatory Pathways of Off-label Drug Use
The ethical risks of off-label clinical use of drugs include many risks, incomplete laws and regulations, difficulties in risk-benefit assessment, and challenges in managing conflict of interest management and obtaining informed consent.
Xuelian TANG +3 more
doaj +1 more source
Background In the rapid evolving landscape of artificial intelligence (AI), scientific publishing is experiencing significant transformations. AI tools, while offering unparalleled efficiencies in paper drafting and peer review, also introduce notable ...
A. Carobene +4 more
semanticscholar +1 more source
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke +4 more
wiley +1 more source
Ethical Culture in Organizations: A Review and Agenda for Future Research
We review and synthesize over two decades of research on ethical culture in organizations, examining eighty-nine relevant scholarly works. Our article discusses the conceptualization of ethical culture in a cross-disciplinary space and its critical role ...
Achinto Roy +3 more
semanticscholar +1 more source
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook +6 more
wiley +1 more source

