Results 41 to 50 of about 1,519,760 (306)
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Keynes and the Ethics of Socialism
Quarterly Journal of Austrian Economics, 2019 This paper examines John Maynard Keynes’s ethical theory and how it relates to his politico-economic thought. Keynes’s ethical theory represents an attack on all general rules.
Edward W. Fuller
doaj +1 more source
, 1989 This paper examines the evidence for Aristotle's theory of comedy in the Poetics and other works. Since he defines comedy in terms of its 'inferior' characters, he cannot have objected in principle to ethical impropriety, obscenity and personal abuse in ...
Heath, M.
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Investigating the Relationship between Core Self-Evaluation and Ethical Leadership with Organizational Financial Performance and Job Performance of Finance Staff [PDF]
حسابداری سلامت, 2018 Introduction: Due to the increasing demand for ethical standards in the current business environment, ethical leadership has particularly been taken into consideration.
M. Hosseini, E. Barzegar
doaj +1 more source
Establishing Ethical Norms: Dignified Justice Theory Perspectives on Ethics and Legal Relations
Rechtsidee: Law Journal, 2022 The relationship between ethical norms and legal norms is different for experts, especially concerning their position. Moreover, legal norms seem to be superior to ethical norms.
Fradhana Putra Disantara +2 more
doaj +1 more source
Moral Realism and Anti-Realism outside the West: A Meta-Ethical Turn in Buddhist Ethics [PDF]
, 2013 In recent years, discussions of Buddhist ethics have increasingly drawn upon the concepts and tools of modern ethical theory, not only to compare Buddhist perspectives with Western moral theories, but also to assess the meta-ethical implications of ...
Davis, Gordon Fraser
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The political dimension of animal ethics in the context of bioethics: problems of integration and future challenges [PDF]
, 2016 Animal ethics has reached a new phase with the development of animal ethical thinking. Topics and problems previously discussed in terms of moral theories and ethical concepts are now being reformulated in terms of political theory and political action ...
Tirado, Carlos R.
core +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source