Results 61 to 70 of about 6,325,010 (302)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Editorial - Guest editors' introduction to a special issue on value theory

open access: yes, 2009
This is an introduction to a special issue of Ethical Theory and Moral Practice that deals with various aspects of value ...
Mulligan, Kevin   +2 more
core  

Ayn Rand’s Egoism: Theory and Analysis [PDF]

open access: yesReligious Inquiries, 2015
Ayn Rand was a Russian-born American philosopher, novelist, and playwright, whose interpretation of ethical egoism is one of the most important interpretations of this theory.
Raham Sharaf   +1 more
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Ethical addresses.

open access: yes, 1908
Caption title.Mode of access ...
American Ethical Union.
core  

TYPES OF ETHICAL THEORY.

open access: yesScience (New York, N.Y.), 1885
n ...
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

The Relationship between Ethical Culture and Unethical Behavior in Work Groups: Testing the Corporate Ethical Virtues Model [PDF]

open access: yes
The Corporate Ethical Virtues Model, which is a model for measuring the ethical culture of organizations, has not been tested on its predictive validity. This study tests the relationship between this model and observed unethical behavior in work groups.
Kaptein, S.P.
core  

Ethics and Mind Theory in Stich's Philosophy; Moral Psychology and Cognitive Sciences United

open access: yesJournal of Philosophical Investigations, 2014
Stephen Stich is one of the most outstanding psychologist and philosophers in the both ethics and mind fields. He merged psychological and philosophical traditions into one and became the source of many studies in moral psychology and philosophy of mind.
Mohammad Hadi Fazeli   +1 more
doaj  

Home - About - Disclaimer - Privacy