Results 71 to 80 of about 6,325,010 (302)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Ethical vs. Non-Ethical – Is There a Difference? Analyzing Performance of Ethical and Non-Ethical Investment Funds [PDF]

Ethical investments have become increasingly popular over the past years. Ethical funds restrict their investment based on environmental, social and/or ethical criteria.
Maria Vikman, Linnéa Lundberg, Jiri Novak   +2 more
core  

Interpretation of the ethical turn of contemporary Western literary theory from the perspective of “New Aristotelism”

Trans/Form/Ação
In the 1980s, the new humanism ethical criticism gradually returned to the mainstream of Western literary theory and criticism academia, realizing the ethical turn of literary theory criticism. The New Aristotelian camp is represented by Wayne Booth and
Qiaozhu Zhang
doaj   +1 more source

The Criterion of Ethical Rules in the Islamic Political System [PDF]

اخلاق وحیانی, 2016
The aim of this paper is to investigate the basis and criterion of ethical values in Islamic political system. The implementation of ethical rules in a political system requires a knowledge of its ethical criterion.
s.fateme faghihi
doaj  

Formulation of “Principle of Compatibility with innate nature” in Imam Khomeini’s Ethical Thought [PDF]

پژوهش‌نامه متین
Imam Khomeini’s ethical theory is an innate nature -centered thought based on which ethics, i.e. ethical insights and tendencies become instances of rules and requisites for an innate desire to love good and perfection and to manifest a hatred of evil ...
Hassan Mahdipour
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Papers from the conference "Ethical imagination and social theory"

, 2012
An introduction to the papers presented at the August 2012 conference "Ethical imagination and social theory" held at Brandbjerg Højskole in ...
Jacob Dahl Rendtorff, Rendtorff, Jacob Dahl, 1965-   +1 more
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Dilema Etis Profesi Akuntan Berdasarkan Aspek Keperilakuan

Jurnal Inovasi Akuntansi
The article discusses ethical dilemmas in the accounting profession, focusing on behavioral aspects. The paper highlights the importance of ethics as a foundational component for responsible societies and sustainable development, especially within ...
Nyoman Yudha Astriayu Widyari, Ida Ayu Komang Tiara Pratistha Sari, Putu Ayu Diah Widari Putri   +2 more
doaj   +1 more source