Results 71 to 80 of about 1,519,760 (306)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Critical Practice Leadership in Post-compulsory Education [PDF]

open access: yes, 2013
This article questions why leaders in post-compulsory education tend not to view leadership research positively or utilise it in improving their practice.
Elliott, Geoffrey
core   +4 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Formulation of “Principle of Compatibility with innate nature” in Imam Khomeini’s Ethical Thought [PDF]

open access: yesپژوهش‌نامه متین
Imam Khomeini’s ethical theory is an innate nature -centered thought based on which ethics, i.e. ethical insights and tendencies become instances of rules and requisites for an innate desire to love good and perfection and to manifest a hatred of evil ...
Hassan Mahdipour
doaj   +1 more source

The Corporate Social Responsibility Debate [PDF]

open access: yes, 2011
The purpose of this study is to evaluate the arguments concerning corporate social responsibility (CSR). The two sides of the debate are stakeholder theory and shareholder theory.
Cheers, Zachary
core   +1 more source

The philosophy of memory today and tomorrow: Editors' introduction [PDF]

open access: yes, 2018
This introductory chapter provides an overview of the chapters making up the book, which are grouped into six sections: challenges and alternatives to the causal theory of memory; activity and passivity in remembering; the affective dimension of memory ...
Debus, Dorothea   +2 more
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Interpretation of the ethical turn of contemporary Western literary theory from the perspective of “New Aristotelism”

open access: yesTrans/Form/Ação
In the 1980s, the new humanism ethical criticism gradually returned to the mainstream of Western literary theory and criticism academia, realizing the ethical turn of literary theory criticism. The New Aristotelian camp is represented by Wayne Booth and
Qiaozhu Zhang
doaj   +1 more source

The Criterion of Ethical Rules in the Islamic Political System [PDF]

open access: yesاخلاق وحیانی, 2016
The aim of this paper is to investigate the basis and criterion of ethical values in Islamic political system. The implementation of ethical rules in a political system requires a knowledge of its ethical criterion.
s.fateme faghihi
doaj  

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